Fmoc-Trp(Boc)-OH CAS 143824-78-6 Purity >98.5% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Fmoc-Trp(Boc)-OH (CAS: 143824-78-6) with high quality. Ruifu Chemical supplys a series of amino acids. We can provide worldwide delivery, competitive price, small and bulk quantities available. Purchase Fmoc-Trp(Boc)-OH, Please contact: alvin@ruifuchem.com
| Chemical Name | Fmoc-Trp(Boc)-OH |
| Synonyms | Fmoc-L-Trp(Boc)-OH; Nα-Fmoc-N(in)-Boc-L-Tryptophan; N(in)-Boc-Nα-Fmoc-L-Tryptophan; N(alpha)-Fmoc-N(in)-Boc-L-Tryptophan; 1-Boc-N-Fmoc-L-Tryptophan; Fmoc-Tryptophan(Boc)-OH; N-(9-fluorenyl)methoxycarbonyl-Trp(Boc)-OH; Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-Butoxycarbonyl-L-Tryptophan |
| Stock Status | In Stock, Production Capacity 20 Tons per Month |
| CAS Number | 143824-78-6 |
| Molecular Formula | C31H30N2O6 |
| Molecular Weight | 526.59 g/mol |
| Melting Point | 86.0~93.0℃ |
| Density | 1.28±0.10 g/cm3 |
| Sensitive | Hygroscopic. Moisture Sensitive |
| Storage Temp. | Cool & Dry Place (2~8℃) |
| COA & MSDS | Available |
| Category | Fmoc-Amino Acids |
| Brand | Ruifu Chemical |
| Items | Inspection Standards | Results |
| Appearance | White to Off-White Powder | White Powder |
| Specific Rotation [α]20/D | -20.0°±4.0° (C=1 in DMF) |
-20.4° |
| Melting Point | 86.0~93.0℃ | 86.2~90.5℃ |
| TLC | ≥98.0% | >98.0% |
| Residual Solvents | Indicate the Last Solvent Used | Ethyl Acetate, Hexane |
| Kaiser Test | <0.05% | <0.05% |
| Water by Karl Fischer | <1.00% | 0.41% |
| Fmoc-β-Ala-OH | <0.50% | Complies |
| Optical Purity | <0.30% D-Enantiomer | 0.19% |
| Clarity of Solution | 0.3 gram in 2ml DMF Clear Solution | Complies |
| Purity / Analysis Method | >98.5% (HPLC) | 99.4% |
| 300 MHz NMR Spectrum 1H | Conforms to Structure | Complies |
| Infrared Spectrum | Conforms to Structure | Complies |
| Conclusion | The product has been tested & complies with the given specifications | |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry (2~8℃) warehouse away from incompatible substances. Protect from light and moisture.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Risk Codes
R36/37/38 - Irritating to eyes, respiratory system and skin.
R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R43 - May cause sensitization by skin contact
Safety Description
S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S27 - Take off immediately all contaminated clothing.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
S37 - Wear suitable gloves.
S24 - Avoid contact with skin.
UN IDs 3077
WGK Germany 3
FLUKA BRAND F CODES 10-21
HS Code 2922491990
Hazard Class 9
Fmoc-Trp(Boc)-OH (CAS: 143824-78-6), Fmoc-amino acids, used in peptide synthesis, used as an organic synthesis intermediate, pharmaceutical intermediate, biochemical reagent or chemical reagent.
Fmoc-Trp(Boc)-OH is a very useful synthetic intermediate. It is used to prepare Trp containing-peptides.
Fmoc-Trp(Boc)-OH can be used for the synthesis of analogs of glucagon-like peptide-1 (GLP-1) for the treatment of type 2 diabetes and various peptides by Fmoc solid phase peptide synthesis (SPPS).
The use of this N-in-Boc protected derivative overcomes most of the problems associated with the preparation of Trp containing-peptides by Fmoc SPPS. Cleavage with TFA generates an N-in-carboxy indole which protects the Trp from alkylation [1, 2, 3] and sulfonation [1, 4, 5, 6, 7]. The N-in-carboxy group is removed under aqueous conditions during normal work-up of the peptide.
