1-Adamantanamine CAS 768-94-5 Purity > 98.0% (GC)
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Ainm Ceimigeach | 1-Adamantanamine |
Co-fhaclan | Amantadine;1-Aminoadamantane;1-Adamantylamine;Adamantan-1-Amine;Tricyclo [3.3.1.13,7] decane-1-amine |
Àireamh CAS | 768-94-5 |
Àireamh CAT | RF-PI2286 |
Inbhe Stoc | Ann an stoc, comas cinneasachaidh 20 MT / Mìos |
Foirmle Molecular | C10H17N |
Cuideam Molecular | 151.25 |
Dùmhlachd | 1.066 g / cm3 |
Mothachail | Air Mothachadh |
Solubility (soluble a-steach) | Methanol;Soluble ann an solventan organach.Neo-sholabailte ann an uisge |
Brand | Ceimigeach Ruifu |
Nì | Sònrachaidhean |
Coltas | Pùdar Buidhe Geal gu Aotrom no Criostal |
Purity / Modh Mion-sgrùdadh | >98.0% (GC) |
Purity / Modh Mion-sgrùdadh | 97.5 ~ 102.5% (Titration le HClO4) |
Rubha leaghaidh | 207.0 ~ 209.0 ℃ |
Taiseachd (KF) | <0.50% |
Fuigheall air Ignition | <0.50% |
Impurities iomlan | <2.00% |
Solubility ann an 1 N HCl | Gun dath gu buidhe buidhe, soilleir gu beagan ceòthach 5% pas |
Spectrum fo-dhearg | A 'gèilleadh ris an Structar |
Spectrum Proton NMR | A 'gèilleadh ris an Structar |
Inbhe deuchainn | Inbhe Iomairt |
Cleachdadh | Cungaidhean-leigheis eadar-mheadhanach |
Pacaid: Botal, poca foil alùmanum, 25kg / druma cairt-bhòrd, no a rèir riatanas luchd-ceannach
Suidheachadh stòraidh:Bùth ann an soithichean dùinte ann an àite fionnar is tioram;Dìon bho sholas is taiseachd
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Tha 1-Adamantanamine, ris an canar cuideachd Amantadine no 1-Aminoadamantane no 1-Adamantylamine (CAS: 768-94-5) ag obair mar inneal-togail ann an ath-bhualadh enantioselective strecker de phosphinoyl imines.Tha e cuideachd feumail airson synthesis derivatives adamantane, ie Amantadine Hydrochloride.Tha 1-Adamantanamine na bhall den chlas de adamantanes a thathas a’ cleachdadh sa ghnìomhachas cungaidh-leigheis mar anti-bhìoras agus droga antiparkinsonian.Tha làimhseachadh Parkinsonism le measgachadh de Levodopa, drogaichean anticholinergic, agus amantadine a 'toirt seachad toraidhean nas fheàrr na bhith a' cleachdadh gin de na drogaichean sin leotha fhèin.Tha e na antagonist lag de ghlacadair glutamate NMDA, a dh’ fhaodadh sgaoileadh dopamine a mheudachadh agus casg a chuir air ath-ghabhail dopamine.Faodaidh an droga cuideachd sgaoileadh norepinephrine a bhrosnachadh bho chrìochan nerve san eanchainn.Faodaidh e dyskinesia de ghalar Pharkinson a làimhseachadh agus dyskinesia adhartachadh às deidh làimhseachadh dopaminergic fad-ùine.
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