2-Chloroadenine CAS 1839-18-5 Assay ≥98.0% (HPLC) Factaraidh
Solaraiche Dèanadair, Àrd-ghlanachd, Riochdachadh Malairteach
Ainm Ceimigeach: 2-Chloroadenine
CAS: 1839-18-5
Ainm Ceimigeach | 2 - Chloroadenine |
Co-fhaclan | 6-Amino-2-Chloropurine;Cladribine EP Impurity B |
Àireamh CAS | 1839-18-5 |
Àireamh CAT | RF-PI513 |
Inbhe Stoc | Ann an stoc, ìre toraidh suas gu tonna |
Foirmle Molecular | C5H4ClN5 |
Cuideam Molecular | 169.57 |
Brand | Ceimigeach Ruifu |
Nì | Sònrachaidhean |
Coltas | Buidhe gu Pùdar Off-White |
Modh Assay / Mion-sgrùdadh | ≥98.0% (HPLC) |
Rubha leaghaidh | ≥300 ℃ |
Call air tiormachadh | ≤0.50% |
Fuigheall air Ignition | ≤0.50% |
Meatailtean Trom (mar Pb) | ≤0.001% |
Neo-dhìomhaireachd iomlan | ≤2.0% |
Inbhe deuchainn | Inbhe Iomairt |
Cleachdadh | Eadar-mheadhanach Clofarabine (CAS: 123318-82-1), Cladribine (CAS: 4291-63-8) |
Pacaid: Botal, poca foil alùmanum, 25kg / druma cairt-bhòrd, no a rèir riatanas luchd-ceannach.
Suidheachadh stòraidh:Bùth ann an soithichean dùinte ann an àite fionnar is tioram;Dìon bho sholas is taiseachd.
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Tha 2-Chloroadenine (CAS: 1839-18-5) air a chleachdadh sa mhòr-chuid mar eadar-mheadhanach de Clofarabine (CAS: 123318-82-1), Cladribine (CAS: 4291-63-8) agus APIan eile.Tha Clofarabine na dhrogaichean anticancer nucleoside purine ùr air a leasachadh gu soirbheachail leis a’ chompanaidh biopharmaceutical Top10 de na Stàitean Aonaichte-Genzyme Corporation.Air 28 Dùbhlachd 2004 chleachd Rianachd Bidhe is Dhrugaichean na SA (FDA) slighe luath airson clofarabine a cheadachadh airson a chuir gu clann le leucemia lymphocytic acute teasairginn no ath-chraoladh.Tha Cladribine (2-chloro-2′-deoxyadenosine) na analogue adenosine-resistant de deoxyadenosine.Tha raon farsaing de ghnìomhachd in vitro aig an droga an aghaidh neoplasms lymphoid agus myeloid.
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