Factaraidh eadar-mheadhanach Afatinib Dimaleate CAS 314771-88-5 Purity > 99.0% (HPLC)
Solarachadh ceimigeach Ruifu eadar-mheadhanach de Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S) -(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino) acetaldehyde Diethyl Acetal CAS 3616-56-6
tar-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Acid Dietylphosphonoacetic CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H) -aon CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S) -N4- (3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S) -N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5
Ainm Ceimigeach | (S) -N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine |
Co-fhaclan | N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-[(3S)-oxolan-3-yl]oxyquinazolin-4-Amine;7-((S) -Tetrahydrofuran-3-yloxy)-4-(3-Chloro-4-Fluorophenyl)amino-6-Nitroquinazoline;Afatinib Impurity |
Àireamh CAS | 314771-88-5 |
Àireamh CAT | RF-PI2027 |
Inbhe Stoc | Ann an stoc, ìre toraidh suas gu tonna |
Foirmle Molecular | C18H14ClFN4O4 |
Cuideam Molecular | 404.78 |
Dùmhlachd | 1.534 ± 0.060 g / cm3 |
Brand | Ceimigeach Ruifu |
Nì | Sònrachaidhean |
Coltas | Buidhe gu Pùdar Buidhe Aotrom |
Purity / Modh Mion-sgrùdadh | > 99.0% (HPLC) |
Call air tiormachadh | <0.50% |
Impurity fa leth | <0.50% |
Impurities iomlan | <1.00% |
Meatailtean Trom | ≤20ppm |
Inbhe deuchainn | Inbhe Iomairt |
Cleachdadh | Eadar-mheadhanach de Afatinib Dimaleate (CAS: 850140-73-7) |
Pacaid: Botal, poca foil alùmanum, 25kg / druma cairt-bhòrd, no a rèir riatanas luchd-ceannach
Suidheachadh stòraidh:Bùth ann an soithichean dùinte ann an àite fionnar is tioram;Dìon bho sholas is taiseachd
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(S) -N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine (CAS: 314771-88-5) air a chleachdadh anns an ullachadh Afatinib Dimaleate (CAS: 850140-73-7).Tha Afatinib na dhroga targaid ùr-ghnàthach an-aghaidh aillse, ginealach ùr de dhroga targaid beòil, a’ chiad dhroga targaid an-aghaidh aillse san t-saoghal a tha ceangailte gu neo-sheasmhach ris an teaghlach ErbB, agus a tha nas èifeachdaiche agus nas cuimsichte A’ cur bacadh air a’ chomharra a bhrosnaicheas fàs cheallan aillse. , a’ lughdachadh no a’ cur dàil air iomadachadh cheallan aillse.Buinidh Afatinib do chlas de dhrogaichean ris an canar luchd-dìon tyrosine kinase.Bidh e ag obair le bhith a’ cur bacadh air gnìomh dà phròtain a tha dlùth cheangailte ris, an receptor factar fàis epidermal (EGFR) agus an gabhadair fàis epidermal daonna 2 (HER2).Air a chleachdadh airson làimhseachadh ciad loidhne air euslaintich le aillse sgamhain meatastatach neo-bheag.Tha Afatinib na dhroga targaid ùr-ghnàthach an-aghaidh aillse, ginealach ùr de dhroga targaid beòil, a’ chiad dhroga targaid an-aghaidh aillse san t-saoghal a tha ceangailte gu neo-sheasmhach ris an teaghlach ErbB, agus a tha nas èifeachdaiche agus nas cuimsichte A’ cur bacadh air a’ chomharra a bhrosnaicheas fàs cheallan aillse. , a’ lughdachadh no a’ cur dàil air iomadachadh cheallan aillse.
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(Dimethylamino) acetaldehyde Diethyl Acetal CAS ...
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(S) -(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2...
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Acid Dietylphosphonoacetic CAS 3095-95-2 Purit ...
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Trans-4-Dimethylaminocrotonic Acid Hydrochlorid...
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Eadar-mheadhanach Afatinib Dimaleate CAS 314771-76-1 ...
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Afatinib Dimaleate Eadar-mheadhanach CAS 314771-88-5...
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N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroqui...
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7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449...
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7-Fluoro-6-Nitroquinazolin-4(1H) -aon CAS 162012 ...
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Afatinib CAS 439081-18-2 Purity > 99.5% (HPLC) F ...
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Afatinib Dimaleate CAS 850140-73-7 Purity > 99.5 ...