Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-26-8 Purity > 99.0% (HPLC) Factaraidh eadar-mheadhanach Nintedanib Esylate
Is e Shanghai Ruifu Chemical Co., Earr am prìomh neach-dèanamh agus solaraiche de Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) le cinneasachadh malairteach àrd-inbhe.
Ainm Ceimigeach | Methyl 2-Oxoindoline-6-Carboxylate |
Co-fhaclan | 2-Oxoindoline-6-Carboxylic Acid Methyl Ester;Methyl Oxindole-6-Carboxylate |
Àireamh CAS | 14192-26-8 |
Àireamh CAT | RF-PI1524 |
Inbhe Stoc | Ann an stoc, ìre toraidh suas gu tonna |
Foirmle Molecular | C10H9 NO3 |
Cuideam Molecular | 191.19 |
Rubha leaghaidh | 184.0 ~ 190.0 ℃ |
Brand | Ceimigeach Ruifu |
Nì | Sònrachaidhean |
Coltas | Buidhe aotrom gu pùdar donn |
Spectrum 1 H NMR | Co-chòrdail ri Structar |
Purity / Modh Mion-sgrùdadh | > 99.0% (HPLC) |
Call air tiormachadh | <1.00% |
Neo-dhìomhaireachd iomlan | <1.00% |
Inbhe deuchainn | Inbhe Iomairt |
Cleachdadh | Eadar-mheadhanach de Nintedanib Esylate (CAS: 656247-18-6) |
Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) Slighe Synthetic
Pacaid: Botal, poca foil alùmanum, 25kg / druma cairt-bhòrd, no a rèir riatanas luchd-ceannach.
Suidheachadh stòraidh:Bùth ann an soithichean dùinte ann an àite fionnar is tioram;Dìon bho sholas is taiseachd.
![1](https://www.ruifuchemical.com/uploads/15.jpg)
![](https://www.ruifuchemical.com/uploads/23.jpg)
Tha Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) na eadar-mheadhanach air a chleachdadh gus Nintedanib Esylate ullachadh (CAS: 656247-18-6).Tha Nintedanib Esylate na neach-dìon angiokinase trì-beòil làidir, beòil air a leasachadh le Boehringer Ingelheim a tha ag amas air slighean proangiogenic agus pro-fibrotic air an eadar-mheadhanachadh leis an gabhadair factar fàis endothelial vascùrach, gabhadair factar fàis fibroblast agus teaghlaichean gabhadair fàis plateletderived, a bharrachd air Src agus Flt-3. cinneach.Chaidh Nintedanib Esylate aontachadh airson làimhseachadh fibrosis sgamhain idiopathic (IPF), suidheachadh anns am bi na sgamhanan a’ fàs mean air mhean thar ùine, le FDA na SA san Dàmhair 2014 agus leis an EMA san Fhaoilleach 2015. Thug an FDA seachad slighe luath nintedanib esylate , ath-sgrùdadh prìomhachais, toradh dìlleachdan, agus sònrachaidhean adhartach.Chaidh aontachadh cuideachd leis an EMA san t-Samhain 2014 airson làimhseachadh aillse sgamhain neo-bheag ann an co-bhonn ri docetaxel às deidh chemotherapy ciad loidhne.
-
Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-26 ...
-
(S) -(-)-Indoline-2-Carboxylic Acid CAS 79815-20 ...
-
(±) -Indoline-2-Carboxylic Acid CAS 78348-24-0 P ...
-
1-Amino-2-Methylindoline Hydrochloride CAS 1027...
-
2-Methylindoline CAS 6872-06-6 Purity > 99.5% (G...
-
5-Bromo-7-Nitroindoline CAS 80166-90-1 Purity > ...
-
Indoline CAS 496-15-1 Purity > 99.0% (GC) Factor ...
-
1-Boc-Indole CAS 75400-67-8 Purity > 96.0% (HPLC ...
-
1-Methylindole CAS 603-76-9 Purity > 98.0% (GC) ...
-
1-Methylindole-3-Carboxaldehyde CAS 138423-98-0...
-
1-Methylindole-3-Carboxaldehyde CAS 19012-03-4 ...
-
1-Methylindole-3-Carboxylic Acid CAS 32387-21-6...
-
(N-Boc-5-bromo-2-indolyl) boronic Acid CAS 47510 ...
-
1- (Phenylsulfonyl) indole CAS 40899-71-6 Purity ...
-
1H-Indole-3-Carbohydrazide CAS 15317-58-5 Purit ...
-
1H-Indole-7-Carboxamide CAS 1670-89-9 Purity > 9...