Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4 Purity > 98.0% (HPLC) Factaraidh Eadar-mheadhanach Lenvatinib Mesylate
Solarachadh ceimigeach Ruifu Lenvatinib Mesylate eadar-mheadhanach le fìor fhìor-ghlan
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cioclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5- (Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Ainm Ceimigeach | Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate |
Co-fhaclan | Impurity Lenvatinib 47;4-Chloro-7-Methoxyquinoline-6-Carboxylic Acid Methyl Ester;4-Chloro-7-Methoxy-6-Quinolinecarboxylic Acid Methyl Ester;Leòmhann-D |
Àireamh CAS | 205448-66-4 |
Àireamh CAT | RF-PI 1970 |
Inbhe Stoc | Ann an stoc, ìre toraidh suas gu tonna |
Foirmle Molecular | C12H10ClNO3 |
Cuideam Molecular | 251.67 |
Rubha Goil | 377.4 ± 37.0 ℃ |
Dùmhlachd | 1.320 ± 0.06 g / cm3 |
Brand | Ceimigeach Ruifu |
Nì | Sònrachaidhean |
Coltas | Pùdar far-gheal gu buidhe soladach |
Spectrum 1 H NMR | Co-chòrdail ri Structar |
Purity / Modh Mion-sgrùdadh | > 98.0% (HPLC) |
Call air tiormachadh | <1.00% |
Impurities iomlan | <2.00% |
Inbhe deuchainn | Inbhe Iomairt |
Cleachdadh | Eadar-mheadhanach / neo-chunbhalachd Lenvatinib Mesylate (CAS: 857890-39-2) |
Pacaid: Botal, poca foil alùmanum, 25kg / druma cairt-bhòrd, no a rèir riatanas luchd-ceannach
Suidheachadh stòraidh:Bùth ann an soithichean dùinte ann an àite fionnar is tioram;Dìon bho sholas is taiseachd
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Tha Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate (CAS: 205448-66-4) na eadar-mheadhanach de Lenvatinib Mesylate (CAS: 857890-39-2).Is e droga aillse thyroid a th ’ann an Lenvatinib a chaidh a leasachadh le Eisai Corporation of Japan (Còd: E7080), a bhuineas don neach-dìon tyrosine kinase ioma-gabhaltach beòil (RTK) agus faodaidh e bacadh a chuir air gnìomhachd kinase den fhactar fàis endothelial vascùrach Receptors R1 (FLT1), VEG-FR2 (KDR), R3 (FLT4).Faodaidh Lenvatinib cuideachd casg a chuir air RTK eile a bhith an sàs ann an angiogenesis pathological, fàs tumhair, agus adhartas aillse ach a-mhàin na gnìomhan cealla àbhaisteach aca a’ toirt a-steach gabhadairean factar fàis fibroblast (FGF) FGFR1, 2, 3, agus 4;gabhadair fàis a thig bho platelet (PDGFR [alpha]), KIT, agus RET.[Comharraidhean]: Tha Lenvatinib freagarrach airson làimhseachadh euslaintich aillse thyroid de sheòrsa ath-chuairteachaidh ionadail no metastasis, seòrsa adhartais agus seòrsa eadar-dhealaichte iodine-teas-teasairginn rèidio-beò.
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