N2-Trityl Olmesartan Acid CAS 752179-89-8 Purity > 98.0% (HPLC) Factaraidh Eadar-mheadhanach Olmesartan Medoxomil
Solarachadh ceimigeach Ruifu Olmesartan Medoxomil eadar-mheadhanach le càileachd àrd:
4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Ethyl 4- (1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Dietyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Trityl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4
Ainm Ceimigeach | N2-Trityl Olmesartan Acid |
Co-fhaclan | Acid Trityl Olmesartan (N2);Olmesartan N2-Trityl Impurity;4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl ] methyl] -1H-Imidazole-5-Carboxylic Acid;4-(2-Hydroxypropan-2-yl)-2-Propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl) methyl)-1H-Imidazole-5-Carboxylic Acid |
Àireamh CAS | 752179-89-8 |
Àireamh CAT | RF-PI1876 |
Inbhe Stoc | Ann an stoc, ìre toraidh suas gu tonna |
Foirmle Molecular | C43H40N6O3 |
Cuideam Molecular | 688.82 |
Brand | Ceimigeach Ruifu |
Nì | Sònrachaidhean |
Coltas | Pùdar Geal gu Off-White |
Purity / Modh Mion-sgrùdadh | > 98.0% (HPLC) |
Call air tiormachadh | <1.00% |
Fuigheall air Ignition | <0.50% |
Impurity singilte | <1.00% |
Neo-dhìomhaireachd iomlan | <2.00% |
Meatailtean Trom (mar Pb) | <20ppm |
Inbhe deuchainn | Inbhe Iomairt |
Cleachdadh | Eadar-mheadhanach de Olmesartan Medoxomil (CAS: 144689-63-4) |
Pacaid: Botal, poca foil alùmanum, 25kg / druma cairt-bhòrd, no a rèir riatanas luchd-ceannach
Suidheachadh stòraidh:Bùth ann an soithichean dùinte ann an àite fionnar is tioram;Dìon bho sholas is taiseachd
Tha N2-Trityl Olmesartan Acid (CAS: 752179-89-8) na eadar-mheadhanach ann an synthesis stuthan co-cheangailte ri Olmesartan Medoxomil (CAS: 144689-63-4).Tha Olmesartan Medoxomil na antagonist gabhadair angiotensin II a chaidh a chleachdadh airson làimhseachadh bruthadh-fala àrd.Tha Olmesartan Medoxomil na prodrug de Olmesartan, na neach-dìon gabhadair angiotensin II seòrsa 1 (AT1) a chuireas casg air fios air ais riaghlaidh àicheil air secretion renin, a’ lughdachadh secretion aldosterone agus a ’leantainn gu lùghdachadh ann an aghaidh vascùrach iomaill (vasodilation).Tha an stuth seo a 'nochdadh gnìomhan antihypertensive, cardioprotective, vasodilatory, agus anti-inflammatory.Faodar Olmesartan Medoxomil a chleachdadh leis fhèin no còmhla ri riochdairean antihypertensive eile.Ann an sgrùdaidhean clionaigeach coimeasach ann an euslaintich le mòr-fhulangas riatanach, lughdaich Olmesartan bruthadh-fala diastolic cuff suidhe mòran nas motha na Losartan, Valdesartan agus Ibesartan, fhad ‘s a bha lughdachadh ann am bruthadh-fala systolic coltach ris a h-uile làimhseachadh.