tert-Butyl 4- (6-Nitropyridin-3-yl) piperazine-1-Carboxylate CAS 571189-16-7 Purity > 98.0% (HPLC) Factaraidh eadar-mheadhanach Palbociclib
Solarachadh ceimigeach Ruifu Palbociclib eadar-mheadhanach co-cheangailte:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4- (6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4- (6-Amino-3-Pyridyl) piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d] pyrimidin-7(8H) -aon CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-aon CAS 1013916-37-4
Ainm Ceimigeach | tert-Butyl 4- (6-Nitropyridin-3-yl)pìobaireachd-1-Carboxylate |
Co-fhaclan | 1-Boc-4- (6-Nitro-3-Pyridyl) piperazine;4-(6-Nitro-3-pyridinyl)-1-Piperazinecarboxylic Acid tert-Butyl Ester;tert-Butyl 4- (6-Nitro-3-Pyridinyl)-1-Piperazinecarboxylate |
Àireamh CAS | 571189-16-7 |
Àireamh CAT | RF-PI1850 |
Inbhe Stoc | Ann an stoc, ìre toraidh suas gu tonna |
Foirmle Molecular | C14H20N4O4 |
Cuideam Molecular | 308.33 |
Brand | Ceimigeach Ruifu |
Nì | Sònrachaidhean |
Coltas | Pùdar aotrom donn gu donn |
Purity / Modh Mion-sgrùdadh | > 98.0% (HPLC) |
LCMS | Co-chòrdail ri Structar |
Call air tiormachadh | <1.00% |
Neo-dhìomhaireachd iomlan | <2.00% |
Inbhe deuchainn | Inbhe Iomairt |
Cleachdadh | Eadar-mheadhanach de Palbociclib (CAS: 571190-30-2) |
Pacaid: Botal, poca foil alùmanum, 25kg / druma cairt-bhòrd, no a rèir riatanas luchd-ceannach
Suidheachadh stòraidh:Bùth ann an soithichean dùinte ann an àite fionnar is tioram;Dìon bho sholas is taiseachd
Tha tert-Butyl 4- (6-nitropyridin-3-yl) piperazine-1-carboxylate (CAS: 571189-16-7) na eadar-mheadhanach de Palbociclib (CAS: 571190-30-2).Tha Palbociclib (ris an canar cuideachd àireamh toinnte PD-0332991) na dhroga deuchainneach airson aillse broilleach a làimhseachadh le Pfizer.Tha e na neach-dìon roghnach de na kinases CDK4 agus CDK6 a tha an urra ri cyclin.Bidh Palbociclib a’ bacadh adhartas cearcall cealla bho ìre G1 gu S le bhith a’ cur bacadh air fosphorylation retinoblastoma CDK4/6 (RB).Chaidh palbociciclibhas a chleachdadh airson aillse broilleach meatastatach dearbhach HER2 àicheil, estrogen receptor (ER) a làimhseachadh.