Factaraidh Trityl Olmesartan Ethyl Ester CAS 144690-33-5 Purity > 98.5% (HPLC)
Solarachadh ceimigeach Ruifu Olmesartan Medoxomil eadar-mheadhanach le càileachd àrd:
4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Ethyl 4- (1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Dietyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Trityl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4
Ainm Ceimigeach | Trityl Olmesartan Ethyl Ester |
Co-fhaclan | Olmesartan Ethyl Ester Trityl Impurity;Olmesartan Medoxomil Impurity 30;4-(1-Hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(Triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl ]methyl] -1H-Imidazole-5-Carboxylic Acid Ethyl Ester;Ethyl 4-(2-hydroxypropan-2-yl)-2-Propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl) )methyl)-1H-Imidazole-5-Carboxylate |
Àireamh CAS | 144690-33-5 |
Àireamh CAT | RF-PI1873 |
Inbhe Stoc | Ann an stoc, ìre toraidh suas gu tonna |
Foirmle Molecular | C45H44N6O3 |
Cuideam Molecular | 716.87 |
Rubha leaghaidh | 161 ℃ |
Dùmhlachd | 1.18 ± 0.1 g / cm3 |
Brand | Ceimigeach Ruifu |
Nì | Sònrachaidhean |
Coltas | Pùdar Geal gu Off-White |
Purity / Modh Mion-sgrùdadh | >98.5% (HPLC) |
Susbaint uisge (KF) | <0.50% |
Fuigheall air Ignition | <0.20% |
Impurity Ⅰ | <0.10% 4-(1-Hydroxy-1-methylpropyl)-2-propyl-1-{[2'-(triphenylmethyl)-1H-tetrazol-5-il] [1,1'-biphenyl] -4-yl ]methyl}-1H-imidazole-5-carboxylic ethyl ester |
Neo-dhìomhaireachd Ⅱ | <0.10% 4-(1-Methoxy-1-methylethyl)-2-propyl-1-{[2'-[1-(triphenylmethyl)-1H-tetrazol-5-il] [1,1'-biphenyl] - 4-yl] methyl}-1H-imidazole-5-carboxylic ethyl ester |
Neo-dhìomhaireachd Ⅲ | <0.50% 4-Isopropenyl-2-propyl-1-{[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl] [1,1'-biphenyl] -4-yl]methyl}-1H -imidazole-5-carboxylic ethyl ester |
Neo-chunbhalachd singilte as àirde eile | <1.00% |
Neo-dhìomhaireachd iomlan | <1.50% |
Inbhe deuchainn | Inbhe Iomairt |
Pacaid: Botal, poca foil alùmanum, 25kg / druma cairt-bhòrd, no a rèir riatanas luchd-ceannach
Suidheachadh stòraidh:Bùth ann an soithichean dùinte ann an àite fionnar is tioram;Dìon bho sholas is taiseachd
Tha Trityl Olmesartan Ethyl Ester (CAS: 144690-33-5) na neo-chunbhalachd de Olmesartan Medoxomil (CAS: 144689-63-4).Tha Olmesartan Medoxomil na antagonist gabhadair angiotensin II a thathar a’ cleachdadh airson bruthadh-fala àrd a làimhseachadh, air a chleachdadh mar dhroga an-aghaidh trom-dhroch bhuaidh.Bidh Olmesartan ag obair le bhith a 'bacadh ceangal angiotensin II gu gabhadairean AT1 ann am fèithean falamh.Le bhith a 'cur bacadh air a' cheangal seach a bhith a 'dèanamh synthesis de angiotensin II, tha Olmesartan a' bacadh fios air ais riaghlaidh àicheil air secretion renin.Chaidh Olmesartan Medoxomil a chuir air bhog anns na SA mar Benicar@, làimhseachadh beòil airson mòr-fhulangas.Tha Olmesartan Medoxomil air a ghnìomhachadh gu luath agus gu tur le ester hydrolysis gu a metabolite gnìomhach, olmesartan, nuair a thèid a ghabhail a-steach bhon t-slighe gastrointestinal.