Trityl Olmesartan Medoxomil CAS 144690-92-6 Purity > 99.0% (HPLC) Factaraidh Eadar-mheadhanach Olmesartan Medoxomil
Solarachadh ceimigeach Ruifu Olmesartan Medoxomil eadar-mheadhanach le càileachd àrd:
4,5-Dimethyl-1,3-Dioxol-2-One (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Ethyl 4- (1-Hydroxy-1-Methylethyl)-2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Dietyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Trityl Olmesartan Ethyl Ester CAS 144690-33-5
Trityl Olmesartan Acid CAS 761404-85-7
N2-Trityl Olmesartan Acid CAS 752179-89-8
Trityl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4
Ainm Ceimigeach | Trityl Olmesartan Medoxomil |
Co-fhaclan | Tritylolmesartan Medoxomil;Triphenyl Methyl Olmesartan;N1-Trityl Olmesartan Medoxomil;Olmesartan Medoxomil EP Impurity D;Olmesartan USP Impurity D;Olmesartan Medoxomil-4;4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-[2-(Triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl ] methyl] -1H-Imidazole-5-Carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester;(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-Hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-) tetrazol-5-il) -[1,1'-biphenyl] -4-il) methyl)-1H-Imidazole-5-Carboxylate |
Àireamh CAS | 144690-92-6 |
Àireamh CAT | RF-PI1874 |
Inbhe Stoc | Ann an stoc, ìre toraidh suas gu tonna |
Foirmle Molecular | C48H44N6O6 |
Cuideam Molecular | 800.90 |
Rubha leaghaidh | 104.0 ~ 106.0 ℃ |
Dùmhlachd | 1.26 ± 0.10 g / cm3 |
Brand | Ceimigeach Ruifu |
Nì | Sònrachaidhean |
Coltas | Pùdar Geal gu Off-White |
Aithneachadh | HPLC;NMR;LC-MS |
Purity / Modh Mion-sgrùdadh | > 99.0% (HPLC) |
Uisge (KF) | <0.50% |
Fuigheall air Ignition | <0.10% |
Stuthan Co-cheangailte | |
Impurity fa leth | <0.50% |
Neo-dhìomhaireachd iomlan | <1.00% |
Meatailtean Trom | <10 ppm |
Inbhe deuchainn | Inbhe Iomairt |
Cleachdadh | Eadar-mheadhanach de Olmesartan Medoxomil (CAS: 144689-63-4) |
Pacaid: Botal, poca foil alùmanum, 25kg / druma cairt-bhòrd, no a rèir riatanas luchd-ceannach
Suidheachadh stòraidh:Bùth ann an soithichean dùinte ann an àite fionnar is tioram;Dìon bho sholas is taiseachd
Tha Trityl Olmesartan Medoxomil (CAS: 144690-92-6) na phrìomh eadar-mheadhanach a thathar a’ cleachdadh ann a bhith ag ullachadh Olmesartan Medoxomil (CAS: 144689-63-4), antagonist receptor angiotension II, a thathar a’ cleachdadh ann an làimhseachadh mòr-fhulangas.Tha Olmesartan Medoxomil na neach-dìon gabhadair angiotensin AT1 cumhachdach agus roghnach le IC50 de 66.2 μM.Tha Olmesartan Medoxomil, prodrug de Olmesartan, na neach-dìon gabhadair angiotensin II seòrsa 1 (AT1) a chuireas casg air fios air ais riaghlaidh àicheil air secretion renin, a ’lughdachadh secretion aldosterone agus a’ leantainn gu lùghdachadh ann an aghaidh vascùrach iomaill (vasodilation).Faodar a chleachdadh leotha fhèin no còmhla ri riochdairean antihypertensive eile.