2,3-Dihydrobenzofuran CAS 496-16-2 Ramelteon Tsabtace Tsabtace>99.0% (GC)
Jagoran Mai ƙira da mai bayarwa, Matsakaicin Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-daya CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2- (2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl) ethanamine Hydrochloride CAS 1053239-39-6
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Sunan Sinadari | 2,3-Dihydrobenzofuran |
Makamantu | Coumaran;2,3-Dihydro-2,3-Benzofuran;2,3-Dihydrobenzo[b]furan;2,3-Dihydro-1-Benzofuran |
Lambar CAS | 496-16-2 |
Lambar CAT | Saukewa: RF2884 |
Matsayin Hannun jari | A Hannun jari, Ƙarfin Samar da Ton 20 a kowane wata |
Tsarin kwayoyin halitta | C8H8O |
Nauyin Kwayoyin Halitta | 120.15 |
Matsayin narkewa | -21 ℃ |
Wurin Tafasa | 188.0 ~ 189.0 ℃ (lit.) |
Wurin Flash | 66 ℃ |
Solubility | Barasa: Mai narkewa |
Bayanin Hazard | Haushi |
Farashin TSCA | Ee |
HS Code | 29329995 |
Adana Yanayin. | An rufe shi a bushe, zafin daki |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Shafe Ruwa mara Launi ko Yellowish |
Tsarkake / Hanyar Bincike | > 99.0% (GC) |
Ruwa (na Karl Fischer) | <0.50% |
Yawan yawa (20 ℃) | 1.065 ~ 1.085 |
Fihirisar Refractive n20/D | 1.547 ~ 1.551 |
Tsaftace Guda Daya | <0.50% |
Jimlar ƙazanta | <1.00% |
Abubuwan da aka bayar na Proton NMR Spectrum | Yayi daidai da Tsarin |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaicin Magunguna na Ramelteon (CAS: 196597-26-9) |
Kunshin: Fluorinated Bottle, 25kg/Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
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2,3-Dihydrobenzofuran (CAS: 496-16-2) ana amfani dashi sosai a cikin haɗin haɗin tricyclic kuma yana da tsaka-tsakin albarkatun kasa don haɗakar wasu magunguna masu mahimmanci.2,3-Dihydrobenzofuran za a iya amfani dashi azaman matsakaici na Ramelteon (CAS: 196597-26-9).Ramelteon, wanda aka tallata shi azaman Rozerem ta Takeda Pharmaceuticals Arewacin Amurka, wakili ne na bacci wanda zaɓi yana ɗaure ga masu karɓar MT1 da MT2 a cikin suprachiasmatic nucleus (SCN), maimakon ɗaure ga masu karɓar GABAA, kamar tare da kwayoyi kamar zolpidem.Sai dai kuma ba ya nuna saurin fara barci ko yawan barcin da mutum ke yi.Hukumar Abinci da Magunguna ta Amurka (FDA) ta amince da ita don amfani na dogon lokaci.Ramelteon baya nuna wani abin da aka yarda da shi ga masu karɓar GABAA, waɗanda ke da alaƙa da anxiolytic, myorelaxant, da tasirin amnesic.Ba kamar yawancin jiyya na rashin barci ba da ke kaiwa ga hadaddun masu karɓa na GABA (g-aminobutyric acid), ramelteon agonist ne na mai karɓar melatonin.Musamman ma, yana da babban zaɓi don ƙananan nau'ikan MT1 da MT2, waɗanda aka sanya su a cikin kiyaye rhythms na circadian, akan mai karɓar MT3 da ke da alhakin sauran ayyukan melatonin.2,3-Dihydrobenzofuran kuma ana amfani dashi a cikin kira na magungunan antitumor benzofuran sulfonylureas, HIV protease inhibitor amino acid hydroxyethylenesulfonyl, matrix metalloproteinase inhibitor aryl sulfinyl isoxime hydroxamic acid, da dai sauransu.