2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 Remdesivir Tsakanin COVID-19
Samar da Kasuwancin Mai ƙera Remdesivir da Matsakaici masu alaƙa tare da Babban inganci
Remdesivir CAS 1809249-37-3
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Trimethylsilyl Cyanide CAS 7677-24-9
4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy) phosphoryl) -L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy) phenoxyphosfinyl] -L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Remdesivir Metabolite (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Matsakaici CAS 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
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Sunan Sinadari | 2,3,5-Tri-O-benzyl-D-ribonolactone |
Makamantu | 2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone;Remdesivir Intermediate |
Lambar CAS | 55094-52-5 |
Lambar CAT | Saukewa: RF-PI301 |
Matsayin Hannun jari | A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram |
Tsarin kwayoyin halitta | Saukewa: C26H26O5 |
Nauyin Kwayoyin Halitta | 418.49 |
Matsayin narkewa | 54.0-55.0 ℃ |
Yanayin Ajiya | Yanayin Daki |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Rawaya ko Fari mai ƙarfi |
Solubility | Mai narkewa a cikin CH2Cl2 kuma Mai narkewa a cikin H2O |
NMR da MS | Yakamata abi |
Ganewa | IR da TLC |
Danshi | ≤1.0% |
Ragowa akan Ignition | ≤0.50% |
Duk wani Rashin Tsabtace Mutum | ≤0.50% |
Karfe masu nauyi | ≤50ppm |
HPLC (210nm) | ≥99.0% |
HPLC (ELSD) | ≥99.0% |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaicin Remdesivir (CAS 1809249-37-3) |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
2,3,5-Tri-O-benzyl-D-ribonolactone (CAS 55094-52-5) matsakaicin Remdesivir ne.Remdesivir (CAS 1809249-37-3) sabon magani ne na rigakafin ƙwayar cuta a cikin nau'in analogues na nucleotide, ana amfani da shi don maganin COVID-19.Remdesivir (GS-5734) wani labari ne na antiviral nucleoside analogue wanda ke hana murine hepatitis virus (MHV) mai kama da EC50 kamar SARS-CoV da MERS-CoV.Coronaviruses (CoVs) tabbataccen hankali ne, ƙwayoyin cuta na RNA masu dunƙule guda ɗaya waɗanda ke cutar da rundunonin dabbobi da yawa.A cikin mutane, an gane CoVs a matsayin yawanci haifar da mura da ciwon huhu har sai bullar cutar sankarau mai tsanani ta coronavirus (SARS-CoV) a cikin 2002 da kuma coronavirus na numfashi na Gabas ta Tsakiya (MERS-CoV) a cikin 2012 daga tushen zoonotic.Remdesivir shine monophosphoramidate prodrug na C-adenosine nucleoside analogue GS-441524.A cikin jinkirin ƙwayar ƙwayar ƙwayar cuta (DBT) da ke kamuwa da MHV, GS-5734 ya hana MHV da karfi fiye da GS-441524, tare da GS-5734 EC50 na 0.03 M. Bugu da ƙari kuma, an ƙayyade ƙimar EC50 bayan jiyya tare da GS-441524 da GS-5734 a cikin al'adun SARS-CoV- da MERS-CoV waɗanda suka kamu da cutar ta farko ta kwayar cutar ta jikin mutum (HAE).