4-Benzyl-2-Hydroxymorpholin-3-daya CAS 287930-73-8 Tsarkake>99.0% (HPLC) Matsakaicin Factory
Jagoran masana'anta da mai kaya
Matsakaici na Aprepitant (CAS: 170729-80-3)
4-Benzyl-2-Hydroxymorpholin-3-daya CAS 287930-73-8
(R) -1-[3,5-Bis (trifluoromethyl) phenyl] ethanol CAS 127852-28-2
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Sunan Sinadari | 4-Benzyl-2-Hydroxymorpholin-3-daya |
Makamantu | 4-Benzyl-2-Hydroxy-Morpholin-3-daya;2-Hydroxy-4- (Phenylmethyl) -3-Morpholinone;Rashin Najasa 48;Fosaprepitant najasa 23;Matsakaicin Matsakaici Ⅱ |
Lambar CAS | 287930-73-8 |
Lambar CAT | Saukewa: RF2660 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C11H13NO3 |
Nauyin Kwayoyin Halitta | 207.23 |
Matsayin narkewa | 134.0 zuwa 138.0 ℃ |
Wurin Tafasa | 441.7± 45.0 ℃ |
Yawan yawa | 1.292± 0.06 g/cm3 |
Solubility a cikin Ruwa | DMSO (Dan kadan), methanol (Dan kadan, mai zafi) |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari zuwa Kashe-Farin Crystal Foda |
Tsarkake / Hanyar Bincike | > 99.0% (HPLC) |
Matsayin narkewa | 134.0 zuwa 138.0 ℃ |
Ruwa (na Karl Fischer) | <0.50% |
Ragowa akan Ignition | <0.20% |
Jimlar ƙazanta | <1.00% |
Abubuwan da aka bayar na Proton NMR Spectrum | Yayi daidai da Tsarin |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaici na Aprepitant (CAS: 170729-80-3) Magungunan Antiemetic |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
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Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
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4-Benzyl-2-Hydroxymorpholin-3-one (CAS: 287930-73-8), shi ne matsakaici na Aprepitant (CAS: 170729-80-3), amfani da matsayin antiemetic kwayoyi.Aprepitant ne neurokinin-1 (NK-1) antagonist receptor antagonist kuma nasa ne a cikin jiyya jamiái na amai a lokacin chemotherapy na ciwon daji.Kamfanin Merck (Jamus) ne ya fara haɓaka shi.A cikin Maris 2003, Hukumar Abinci da Magunguna ta Amurka ta amince da shi don amfani da shi wajen maganin amai na chemotherapy.Wannan samfurin yana da babban zaɓin alaƙa ga ɗan adam yayin da yake da ƙarancin kusanci ga serotonin, dopamine da alaƙar mai karɓar glucocorticoid.Aprepitant, lokacin da aka haɗe tare da masu hana masu karɓa na 5-HT3 (irin su ondansetron hydrochloride) da corticosteroid dexamethasone, na iya ƙara rage cisplatin-induced m da (ko) jinkirta emesis.Yin amfani da wannan magani kadai na iya samun wasu sakamako na rigakafi.