4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Tsarkake>98.5% (HPLC) Lenvatinib Mesylate Intermediate Factory

Takaitaccen Bayani:

Suna: 4-Chloro-7-Methoxyquinoline-6-Carboxamide

Saukewa: 417721-36

Tsafta:> 98.5% (HPLC)

Bayyanar: Kashe-Fara zuwa Foda Rawaya mai Haske

Matsakaicin Lenvatinib Mesylate CAS 857890-39-2

Kyakkyawan inganci, Samar da Kasuwanci

E-Mail: alvin@ruifuchem.com


Cikakken Bayani

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Bayani:

Abubuwan Sinadarai:

Sunan Sinadari 4-Chloro-7-Methoxyquinoline-6-Carboxamide
Makamantu 4-Chloro-7-Methoxy-6-Quinolinecarboxamide;Lenvatinib rashin tsarki 12;Lenvatinib Rashin Tsabtace B;Lenvatinib rashin tsabta LFS-B
Lambar CAS 417721-36-9
Lambar CAT Saukewa: RF-PI1971
Matsayin Hannun jari A cikin Hannun jari, Ƙarfin Samar da 50MT/Shekara
Tsarin kwayoyin halitta Saukewa: C11H9ClN2O2
Nauyin Kwayoyin Halitta 236.65
Matsayin narkewa > 205 ℃ (Dec.)
Yawan yawa 1.380± 0.060 g/cm3
Alamar Ruifu Chemical

Ƙayyadaddun bayanai:

Abu Ƙayyadaddun bayanai
Bayyanar Kashe-Fara Zuwa Hasken Foda na Yellow
Tsarkake / Hanyar Bincike 98.5% (HPLC)
Asara akan bushewa <0.50%
Ragowa akan Ignition <0.50%
Jimlar ƙazanta <1.50%
Abubuwan da aka bayar na Proton NMR Spectrum Yayi daidai da Tsarin
Matsayin Gwaji Matsayin Kasuwanci
Amfani Matsakaicin Lenvatinib Mesylate (CAS: 857890-39-2)

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi

Amfani:

1

FAQ:

Aikace-aikace:

4-Chloro-7-Methoxyquinoline-6-Carboxamide (CAS: 417721-36-9) yawanci ana amfani dashi azaman tsaka-tsakin Lenvatinib Mesylate (CAS: 857890-39-2).Eisai Inc ya haɓaka, lenvatinib mesylate shine mai hanawa na endothelial endothelial growth factor (VEGF) mai hanawa wanda ke da aiki akan VEGF subtypes 1, 2, da 3 kuma FDA ta amince da ita a cikin 2015 don maganin bambance-bambancen ciwon daji na thyroid wanda shine ko dai a gida. mai-maitawa, metastatic, ko ci gaba kuma bai amsa maganin iodine na rediyoaktif ba.A cikin Mayu 2016, FDA ta amince da miyagun ƙwayoyi a matsayin haɗin haɗin gwiwa tare da everolimus don maganin ciwon daji na ƙwayar ƙwayar ƙwayar ƙwayar cuta.Saboda VEGF (da masu karɓar haɓakar haɓakar fibroblast, wanda aka sani da FGFRs) ana tsammanin za su taka rawa a cikin hanyoyin sigina na zuciya, VEGF2R da hana FGFR sune hanyoyin da ke bayan tasirin sakamako na farko na lenvatinib mesylate, wanda shine hauhawar jini.

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