5- (2-Fluorophenyl) -1H-Pyrrole-3-Carbaldehyde CAS 881674-56-2 Vonoprazan Fumarate Tsabtace Tsabtace ≥99.0%
Bayar da Vonoprazan Fumarate da Matsakaicin Mahimmanci
5- (2-Fluorophenyl) pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Sunan Sinadari | 5- (2-Fluorophenyl) -1H-Pyrrole-3-Carbaldehyde |
| Makamantu | Vonoprazan Fumarate (TAK-438) Matsakaici 3 |
| Lambar CAS | 881674-56-2 |
| Lambar CAT | Saukewa: RF-PI330 |
| Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
| Tsarin kwayoyin halitta | Saukewa: C11H8FNO |
| Nauyin Kwayoyin Halitta | 189.19 |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Yellow zuwa Brown Foda |
| Matsayin narkewa | 122.0 ~ 131.0 ℃ |
| Shaida: RT (HPLC) | Yi Daidai Da Ƙimar Magana |
| Asara Kan bushewa | ≤0.50% |
| Ragowa Akan ƙonewa | ≤0.50% |
| Abubuwa masu alaƙa | |
| Tsafta | ≥99.0% |
| Duk Wani Rashin Tsabtace Guda Daya | ≤0.50% |
| Jimlar ƙazanta | ≤1.0% |
| Matsayin Gwaji | Matsayin Kasuwanci |
| Amfani | Matsakaicin Vonoprazan Fumarate (TAK-438) (CAS 881681-01-2) |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
5- (2-Fluorophenyl) -1H-Pyrrole-3-Carbaldehyde (CAS 881674-56-2) yana aiki azaman reagent a cikin shirye-shiryen roba na abubuwan da suka samo asali na pyrrole kamar potassium-competitive acid blocker (P-CAB).5- (2-Fluorophenyl) pyrrole-3-Carboxaldehyde shine matsakaici na Vonoprazan Fumarate (CAS 1260141-27-2).Vonoprazan fumarate (Takecab®), wanda Takeda da Otsuka suka gano kuma suka haɓaka, PMDA na Japan ya amince da shi a cikin Disamba 2014, kuma ana nuna shi don maganin cututtukan ciki, ulcer na duodenal da reflux esophagitis.Vonoprazan fumarate yana da sabon tsarin aikin da ake kira potassium-competitive acid blockers, wanda ke hana daurin potassium ions zuwa H+, K+-ATPase (wanda aka fi sani da famfo proton) a matakin karshe na fitar da acid na ciki a cikin sel parietal na ciki.Vonoprazan baya hana ayyukan Na +, K+-ATPase ko da a lokuta 500 mafi girma fiye da na ƙimar su IC50 akan aikin H+, K+-ATPase na ciki.Bugu da ƙari kuma, miyagun ƙwayoyi ba shi da tasiri ta hanyar asiri na ciki, sabanin PPIs.
