5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4 Dapagliflozin Intermediate Factory
Samar da Maƙera, Babban Tsafta, Samar da Kasuwanci
Dapagliflozin (CAS: 461432-26-8) Matsakaici masu alaƙa:
5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
Sunan Sinadari | 5-Bromo-2-Chlorobenzoic Acid |
Makamantu | 2-Chloro-5-Bromobenzoic Acid |
Lambar CAS | 21739-92-4 |
Lambar CAT | Saukewa: RF-PI439 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C7H4BrClO2 |
Nauyin Kwayoyin Halitta | 235.46 |
Matsayin narkewa | 154.0 zuwa 156.0 ℃ (lit.) |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Kashe-Fara Zuwa Hasken Foda na Yellow |
Assay | ≥99.0% |
Ruwa (KF) | ≤0.50% |
Ragowa akan Ignition | ≤0.30% |
2-Chlorobenzoic Acid | ≤0.30% |
2-Chloro-3-Bromobenzoic Acid | ≤0.30% |
Jimlar ƙazanta | ≤1.0% |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaicin Dapagliflozin (CAS: 461432-26-8), nau'in ciwon sukari na II |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi.
5-Bromo-2-Chlorobenzoic Acid (CAS: 21739-92-4) ana amfani dashi azaman kayan farawa a cikin haɗin Dapagliflozin (CAS: 461432-26-8), zaɓin sodium-glucose cotransporter-2 inhibitor wanda ke rage ƙwayar koda. reabsorption na glucose kuma ana amfani dashi don kula da marasa lafiya masu ciwon sukari na II.Dapagliflozin shine mai hanawa SGLT-2 (SLC5A2) mai ƙarfi da zaɓi tare da EC50 na 1.1 nM.Yana da kyau permeability a fadin Caco-2 cell membranes kuma shi ne wani substrate ga P-glycoprotein (P-gp).An amince da Dapagliflozin a cikin 2012 ta FDA.