6-O-Methylguanine CAS 20535-83-5 Nelzarabine Intermediate Factory
Ƙarfafawa Tare da Babban Tsafta, Samar da Kasuwanci
Sunan Chemical: 6-O-Methylguanine
Saukewa: 20535-83-5
| Sunan Sinadari | 6-O-Methylguanine |
| Makamantu | 2-Amino-6-Methoxypurine |
| Lambar CAS | 20535-83-5 |
| Lambar CAT | Saukewa: RF-PI509 |
| Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
| Tsarin kwayoyin halitta | Saukewa: C6H7N5O |
| Nauyin Kwayoyin Halitta | 165.16 |
| Matsayin narkewa | > 300 ℃ (lit.) |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Kashe-White Crystalline Foda |
| Hanyar Assay / Analysis | ≥98.5% (HPLC) |
| Asara akan bushewa | ≤0.50% |
| Ragowa akan Ignition | ≤0.50% |
| Jimlar ƙazanta | ≤1.5% |
| Matsayin Gwaji | Matsayin Kasuwanci |
| Amfani | Matsakaicin Nelzarabine (CAS: 121032-29-9), T-ALL & T-LBL |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi.
6-O-Methylguanine (CAS: 20535-83-5) za a iya amfani dashi azaman tsaka-tsaki a cikin haɗin Nelzarabine (CAS: 121032-29-9).Nelarabine prodrug ne don deoxyguanosine analogue-9-beta-D-arabinofuranosyl guanine (ara-G).Nelarabine demethylates a cikin rawar adenosine deaminase (ADA) kuma ya juya zuwa ara-G.GlaxoSmithKline ya fara haɓaka Nelarabine cikin nasara.A ranar 28 ga Oktoba, 2005 a ƙarƙashin amincewar Hukumar Abinci da Magunguna ta Amurka, ta zama sabon magani don warkar da cutar sankarar jini mai saurin jini ta T-cell (T-ALL) da T-Cells lymphoblasticlymphoma (T-LBL) waɗanda ke da juriya ga aƙalla. nau'i biyu na tsarin chemotherapy ko sake dawowa bayan jiyya na farko.Wannan sabon magani da aka jera a hukumance a Amurka a cikin 2006.
