7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-daya CAS 160129-45-3 Tolvaptan Intermediate
Samar da Mai ƙira, Babban inganci, Samar da Kasuwanci
Tolvaptan da Matsakaici masu alaƙa:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-daya CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
Sunan Sinadari | 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-daya |
Makamantu | 7-Chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-daya;7-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H) -daya |
Lambar CAS | 160129-45-3 |
Lambar CAT | Saukewa: RF-PI395 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C10H10ClNO |
Nauyin Kwayoyin Halitta | 195.65 |
Matsayin narkewa | 103.0 zuwa 107.0 ℃ |
Solubility | Mai narkewa a cikin methanol |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Kore Mai Haske Zuwa Hasken Farin Ruwa |
Hanyoyin Ganewa | NMR, HPLC |
Tsarkake / Hanyar Bincike | ≥99.0% (HPLC) |
Asara akan bushewa | ≤1.0% |
Ragowa akan Ignition | ≤0.50% |
Duk Wani Rashin Tsabtace Guda Daya | ≤0.50% |
Jimlar ƙazanta | ≤1.0% |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaicin Tolvaptan (CAS 150683-30-0), jiyya na Hyponatremia |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi.
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7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one (CAS 160129-45-3) matsakaita ne a cikin hadawar Tolvaptan (CAS 150683-30-0).Tolvaptan zaɓi ne, gasa na baka mai aiki mara ƙarfi arginine vasopressin V2 antagonist mai karɓa tare da IC50 na 1.28µM don hana AVP-induced tara platelet.Ana amfani da Tolvaptan don magance hyponatremia mai alaƙa da gazawar zuciya, cirrhosis, da ciwo na hormone antidiuretic da bai dace ba.Tolvaptan kuma yana cikin gwaje-gwajen asibiti cikin sauri don cutar koda polycystic.Jiyya tare da Tolvaptan yana haifar da raguwar nauyin jiki mai sauri da ɗorewa tare da haɓaka fitowar fitsari, ingantawa da/ko daidaita sinadarin sodium a cikin marasa lafiya na hyponatremic, yana rage alamun da alamun cunkoso kuma yana ƙara ƙishirwa.