7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2 Tsarkake>99.0% (HPLC) Afatinib Dimaleate Matsakaici Factory Featured Image

7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2 Tsarkake>99.0% (HPLC) Afatinib Dimaleate Tsakanin Factory

Takaitaccen Bayani:

Suna: 7-Chloro-6-Nitro-4-Hydroxyquinazoline

Saukewa: 53449-14-2

Tsafta:> 99.0% (HPLC)

Bayyanar: Rawaya mai haske zuwa Foda mai haske

Matsakaicin Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

Aika mana imel

Cikakken Bayani

Samfura masu dangantaka

Tags samfurin

Bayani:

Ruifu Chemical Supply Intermediates of Afatinib
Afatirib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino) acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H) -daya CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl) oxy) quinazoline-4,6-DiamineSaukewa: CAS314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy) quinazolin-4-AmineSaukewa: CAS314771-88-5

Abubuwan Sinadarai:

Sunan Sinadari	7-Chloro-6-Nitro-4-Hydroxyquinazoline
Makamantu	7-Chloro-4-Hydroxy-6-Nitroquinazoline;7-Chloro-6-Nitro-4-Quinazolinol;7-Chloro-6-Nitro-4-Quinazolinone;7-Chloro-6-Nitro-4(3H)-Quinazolinone;7-Chloro-6-Nitro-3,4-Dihydroquinazolin-4-daya;7-Chloro-6-Nitroquinazolin-4(3H) -daya
Lambar CAS	53449-14-2
Lambar CAT	Saukewa: RF-PI2030
Matsayin Hannun jari	A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton
Tsarin kwayoyin halitta	Saukewa: C8H4ClN3O3
Nauyin Kwayoyin Halitta	225.59
Hankali	Zafi Sensitive
Solubility	Dan Soluble a Dimethylformamide
Alamar	Ruifu Chemical

Ƙayyadaddun bayanai:

Abu	Ƙayyadaddun bayanai
Bayyanar	Rawaya Mai Haske Zuwa Hasken Foda
Identification (HPLC)	Lokacin Riƙon Samfurin Ya Kamata Yayi Daidai da Ma'auni
Tsarkake / Hanyar Bincike	> 99.0% (HPLC)
Matsayin narkewa	300.0 ~ 303.0 ℃
Abubuwan Ruwa (KF)	<0.50%
Ragowa akan Ignition	<0.30%
Rashin tsarki 1	<0.50% (7-Chloro-4-Hydroxyquinazoline CAS: 31374-18-2)
Rashin tsarki 2	<0.50% (5,7-Dichloro-4[1H] quinazolinone)
Rashin tsarki 3	<1.00% (7-Chloro-8-Nitro-4[1H] quinazolinone)
Sauran Rashin Tsabtace Guda Daya	<0.20%
Jimlar ƙazanta	<1.00%
Karfe masu nauyi (kamar Pb)	<20ppm
Infrared Spectrum	Yayi daidai da Tsarin
Abubuwan da aka bayar na Proton NMR Spectrum	Abubuwan da aka bayar na Proton NMR Spectrum
Matsayin Gwaji	Matsayin Kasuwanci
Amfani	Matsakaicin Afatinib, Afatinib Dimaleate

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi

Amfani:

FAQ:

Aikace-aikace:

7-Chloro-6-Nitro-4-Hydroxyquinazoline (CAS: 53449-14-2) matsakanci ne na Afatinib Dimaleate (CAS: 850140-73-7).Afatinib dangin ErbB ne na masu toshe hanyoyin da ba za a iya jurewa ba waɗanda ke hana watsa bayanai da kuma toshe manyan hanyoyin da ke tattare da haɓakar ƙwayoyin cutar kansa da rarrabuwa.Saboda tsarin watsa bayanan dangi na ErbB na iya haifar da homodimers da yawa da heterodimers, hanawa dangin ErbB da yawa lokaci guda (kamar EGFR, HER2, ErbB3 da ErbB4) na iya katse watsa bayanan ƙasa yadda ya kamata.Ana amfani da Afatinib don magance wani nau'in ciwon daji na huhu (wanda ba ƙananan ƙwayar cuta ba) wanda ya bazu zuwa wasu sassan jiki.Yana cikin rukunin magungunan da aka sani da masu hana kinase.Yana aiki ta ragewa ko dakatar da ci gaban ƙwayoyin cutar kansa.Yana ɗaure da wani furotin (Epidermal receptor-EGFR) a wasu ciwace-ciwacen daji.