7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Tsarkake Tsarkake Tsarkakewa
Samar da Mai ƙera Irinotecan da Matsakaici masu alaƙa:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Sunan Sinadari | 7-Ethyl-10-Hydroxycamptothecin |
| Makamantu | Farashin SN-38 |
| Lambar CAS | 86639-52-3 |
| Lambar CAT | Saukewa: RF-PI242 |
| Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
| Tsarin kwayoyin halitta | Saukewa: C22H20N2O5 |
| Nauyin Kwayoyin Halitta | 392.41 |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Farin Lu'ulu'u Mai Haske Rawaya Mai Haske |
| Identification (IR, UV) | (1) Ultraviolet ray sha bakan bakan daidai da bukatun (2) Infrared ray absorption spectrum concordant tare da ma'auni bakan bakan zai bi yarda da gwaje-gwaje. |
| Matsayin narkewa | 228.0 ~ 235.0 ℃ |
| Abubuwa masu alaƙa | ≤1.5% |
| 10-Hydroxycamptothecin | ≤0.30% |
| 7-Cthylcamptothecin | ≤0.70% |
| Matsakaicin rashin tsarkin da ba a sani ba | ≤0.50% |
| Asara akan bushewa | ≤1.0% |
| Karfe masu nauyi | ≤10pm |
| Ragowa akan Ignition | ≤0.10% |
| Bayyanar Magani | Share |
| Assay | ≥98.0% (HPLC) |
| Matsayin Gwaji | Matsayin Kasuwanci |
| Amfani | Matsakaicin Pharmaceutical na Irinotecan |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta kuma mai samar da 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) tare da babban inganci.7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) wani aiki metabolite ne na Topoisomerase I inhibitor Irinotecan.SN-38 (NK012) yana hana DNA da RNA kira tare da IC50s na 0.077 da 1.3 μM, bi da bi.7-Ethyl-10-Hydroxycamptothecin (SN-38), shi ne mai aiki metabolite na Irinotecan, wani semisynthetic wanda aka samu na camptothecin, wani quinoline tushen alkaloid samu a cikin haushi na kasar Sin camptotheca itace da kuma Asian nothapodytes itace.Ko da yake 7-Ethyl-10-Hydroxycamptothecin yana da ƙarfi har sau 1,000 fiye da Irinotecan, ba a canza shi zuwa ɗan takarar magani mai inganci ba saboda ba ya narkewa.A halin yanzu ana fuskantar gwaji na asibiti a hade tare da wasu nau'ikan da zasu iya ba da damar yin amfani da shi azaman maganin antineoplastic.
