7-Fluoro-6-Nitroquinazolin-4(1H) -daya CAS 162012-69-3 Tsarkake>99.0% (HPLC) Afatinib Dimaleate Matsakaici Factory Featured Image

7-Fluoro-6-Nitroquinazolin-4(1H) -daya CAS 162012-69-3 Tsarkake>99.0% (HPLC) Afatinib Dimaleate Tsakanin Factory

Takaitaccen Bayani:

Sunan Sinadari: 7-Fluoro-6-Nitroquinazolin-4(1H) -daya

Saukewa: 162012-69-3

Tsafta:> 99.0% (HPLC)

Jawo zuwa Jajayen Crystal Crystal ko Foda

Matsakaicin Afatinib Dimaleate (CAS: 850140-73-7)

Kyakkyawan inganci, Samar da Kasuwanci

E-Mail: alvin@ruifuchem.com

Aika mana imel

Cikakken Bayani

Samfura masu dangantaka

Tags samfurin

Bayani:

Ruifu Chemical Supply Intermediates of Afatinib
Afatirib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino) acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H) -daya CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl) oxy) quinazoline-4,6-DiamineSaukewa: CAS314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy) quinazolin-4-AmineSaukewa: CAS314771-88-5

Abubuwan Sinadarai:

Sunan Sinadari	7-Fluoro-6-Nitroquinazolin-4(1H) -daya
Makamantu	7-Fluoro-6-Nitroquinazolin-4(3H) -daya;7-Fluoro-4-Hydroxy-6-Nitroquinazoline;7-Fluoro-6-Nitroquinazolin-4-ol;7-Fluoro-6-Nitro-4-Hydroxyquinazoline;7-Fluoro-6-Nitro-1H-Quinazolin-4-daya
Lambar CAS	162012-69-3
Lambar CAT	Saukewa: RF-PI2025
Matsayin Hannun jari	A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton
Tsarin kwayoyin halitta	Saukewa: C8H4FN3O3
Nauyin Kwayoyin Halitta	209.13
Alamar	Ruifu Chemical

Ƙayyadaddun bayanai:

Abu	Ƙayyadaddun bayanai
Bayyanar	Jawo zuwa Jajayen Crystal Crystal ko Foda
1 H NMR Spectrum	Daidaita Da Tsarin
Tsarkake / Hanyar Bincike	> 99.0% (HPLC)
Asara akan bushewa	<0.50%
Jimlar ƙazanta	<1.00%
Abubuwan da aka bayar na Proton NMR Spectrum	Yayi daidai da Tsarin
Matsayin Gwaji	Matsayin Kasuwanci
Amfani	Matsakaicin Afatinib Dimaleate (CAS: 850140-73-7)

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi

Amfani:

FAQ:

Aikace-aikace:

7-Fluoro-6-Nitroquinazolin-4(1H) -daya (CAS: 162012-69-3) matsakaici ne na Afatinib Dimaleate (CAS: 850140-73-7).Afatinib dangin ErbB ne na masu toshe hanyoyin da ba za a iya jurewa ba waɗanda ke hana watsa bayanai da kuma toshe manyan hanyoyin da ke tattare da haɓakar ƙwayoyin cutar kansa da rarrabuwa.Saboda tsarin watsa bayanan dangi na ErbB na iya haifar da homodimers da yawa da heterodimers, hanawa dangin ErbB da yawa lokaci guda (kamar EGFR, HER2, ErbB3 da ErbB4) na iya katse watsa bayanan ƙasa yadda ya kamata.Afatinib magani ne da aka amince da shi don maganin cutar sankarau mara ƙarami (NSCLC), wanda Boehringer Ingelheim ya haɓaka.Yana aiki azaman mai hana angiokinase.Kamar lapatinib da neratinib, afatinib shine mai hanawa na tyrosine kinase (TKI) wanda kuma ba zai iya jurewa ba yana hana mai karɓar haɓakar haɓakar haɓakar ɗan adam 2 (Her2) da mai karɓar haɓakar haɓakar haɓakar epidermal (EGFR) kinases.Afatinib ba wai kawai yana aiki ne da maye gurbi na EGFR wanda tsaran farko na TKIs likeerlotinib ko gefitinib ke niyya ba, har ma da waɗanda basu kula da waɗannan ƙa'idodi na yau da kullun ba.Saboda ƙarin ayyukansa akan Her2, ana bincikar cutar kansar nono da sauran cututtukan daji na EGFR da Her2.