7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1 Tsarkake>99.0% (GC) Agomelatine Matsakaici
Jagoran Mai ƙira da Mai ba da Tallafin Agomelatine Intermediates
Agomelatine CAS 138112-76-2
7-Methoxy-1-Tetralone CAS 6836-19-7
7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
Please contact: alvin@ruifuchem.com
| Sunan Sinadari | 7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester |
| Makamantu | Ethyl 2- (7-Methoxynaphthalen-1-yl) acetate |
| Lambar CAS | 6836-21-1 |
| Lambar CAT | Saukewa: RF2687 |
| Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
| Tsarin kwayoyin halitta | Saukewa: C15H16O3 |
| Nauyin Kwayoyin Halitta | 244.29 |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Ruwan Rawaya Mai Haske |
| Tsarkake / Hanyar Bincike | > 99.0% (GC) |
| Ruwa (na Karl Fischer) | <0.50% |
| Abubuwa masu alaƙa | <1.00% |
| Infrared Spectrum | Yayi daidai da Tsarin |
| Farashin NMR Spectrum | Yayi daidai da Tsarin |
| Matsayin Gwaji | Matsayin Kasuwanci |
| Amfani | Matsakaicin Magunguna na Agomelatine (CAS: 138112-76-2) |
Kunshin: Fluorinated Kwalba, 25kg / Ganga, ko bisa ga bukatun abokin ciniki
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7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester (CAS: 6836-21-1) mai amfani ne mai amfani da kwayoyin halitta na wucin gadi, ana iya amfani da shi azaman matsakaicin magunguna na Agomelatine (CAS: 138112-76-2).Agomelatine, wanda Kamfanin Servier na Faransa ya haɓaka, shine farkon masu karɓar melatonin a duniya MT1 da MT2 agonist na maganin damuwa.Ya shafi lura da manya marasa lafiya da matsananciyar damuwa.Agomelatine magani ne na antidepressant.Agomelatine agonist ne na melatonin (MT) masu karɓa da kuma abin da aka samo daga melatonin.Yana ɗaure ga masu karɓa na MT1 da MT2 (Kis = 0.14 da 0.41 nM, bi da bi) kuma yana da ƙimar EC50 na 0.1 nM a cikin gwajin ɗauri na [35S] GTPγS ta amfani da ƙwayoyin CHO da ke bayyana masu karɓar MT2.An rarraba shi azaman disinhibitor na norepinephrine-dopamine (NDDI) saboda ƙiyayyar mai karɓar 5-HT2C.Kunna masu karɓar 5-HT2C ta hanyar serotonin yana hana dopamine da sakin norepinephrine.
