Afatinib Dimaleate Intermediate CAS 314771-88-5 Tsarkake>99.0% (HPLC) Factory
Ruifu Chemical Supply Intermediates of Afatinib
Afatirib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino) acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H) -daya CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl) oxy) quinazoline-4,6-DiamineSaukewa: CAS314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy) quinazolin-4-AmineSaukewa: CAS314771-88-5
Sunan Sinadari | (S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy) quinazolin-4-Amine |
Makamantu | N- (3-Chloro-4-Fluorophenyl) -6-Nitro-7-[(3S) -oxolan-3-yl] oxyquinazolin-4-Amine;7-((S) -Tetrahydrofuran-3-yloxy -4- (3-Chloro-4-Fluorophenyl) amino-6-Nitroquinazoline;Afatinib rashin tsarki |
Lambar CAS | 314771-88-5 |
Lambar CAT | Saukewa: RF-PI2027 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C18H14ClFN4O4 |
Nauyin Kwayoyin Halitta | 404.78 |
Yawan yawa | 1.534± 0.060 g/cm3 |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Rawaya Zuwa Haske Jawo Foda |
Tsarkake / Hanyar Bincike | > 99.0% (HPLC) |
Asara akan bushewa | <0.50% |
Rashin Tsabtace Mutum | <0.50% |
Jimlar ƙazanta | <1.00% |
Karfe masu nauyi | ≤20ppm |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaicin Afatinib Dimaleate (CAS: 850140-73-7) |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
(S) -N-(3-Chloro-4-Fluorophenyl) -6-Nitro-7-((Tetrahydrofuran-3-yl) oxy) quinazolin-4-Amine (CAS: 314771-88-5) ana amfani dashi a cikin shiri na Afatinib Dimaleate (CAS: 850140-73-7).Afatinib sabon magani ne na rigakafin cutar kansa, sabon ƙarni na maganin da ake nufi na baka, maganin cutar kansa na farko a duniya wanda ba zai sake komawa ba ga dangin ErbB, kuma ya fi inganci da niyya Yana toshe siginar da ke haifar da haɓakar ƙwayoyin cutar kansa. , ragewa ko jinkirta yaduwar kwayoyin cutar kansa.Afatinib na cikin rukunin magungunan da aka sani da masu hana tyrosine kinase.Yana aiki ta hanyar toshe aikin sunadaran da ke da alaƙa da juna, mai karɓar haɓakar haɓakar haɓakar epidermal (EGFR) da mai karɓar haɓakar haɓakar haɓakar ɗan adam 2 (HER2).An yi amfani da shi don jiyya na farko na marasa lafiya tare da ciwon huhu na huhu wanda ba ƙananan ƙananan ƙwayoyin cuta ba.Afatinib sabon magani ne na rigakafin cutar kansa, sabon ƙarni na maganin da ake nufi na baka, maganin cutar kansa na farko a duniya wanda ba zai sake komawa ba ga dangin ErbB, kuma ya fi inganci da niyya Yana toshe siginar da ke haifar da haɓakar ƙwayoyin cutar kansa. , ragewa ko jinkirta yaduwar kwayoyin cutar kansa.