Argatroban CAS 74863-84-6 API Factory High Tsarkake Anticoagulant
Matsakaicin Matsakaici Mai alaƙa da Samfuran Argatroban:
Ethyl (2R,4R) -4-Methyl-2-Piperidinecarboxylate CAS 74892-82-3
N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester CAS 74874-09-2
3-Methyl-8-Quinolinesulphonyl Chloride CAS 74863-82-4
Argatroban Monohydrate CAS 141396-28-3
Argatroban Anhydrous CAS 74863-84-6
Sunan Sinadari | Argatroban |
Makamantu | Argatroban Anhydrous |
Lambar CAS | 74863-84-6 |
Lambar CAT | RF-API67 |
Matsayin Hannun jari | A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram |
Tsarin kwayoyin halitta | Saukewa: C23H36N6O5S |
Nauyin Kwayoyin Halitta | 508.63 |
Matsayin narkewa | 188.0 ~ 189.0 ℃ |
Wurin Tafasa | 801.3ºC a 760 mmHg |
Yawan yawa | 1.47 g/cm 3 |
Yanayin jigilar kaya | An aika Karkashin Zazzabin yanayi |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari zuwa Kashe-White Crystalline Foda |
Bayanin HPLC | Lokacin riƙewa na ƙa'ida mafi girma da aka samu daga maganin Gwajin ya dace da wanda aka samu daga daidaitaccen bayani, azaman gwaji a cikin Assay |
Gano IR | Ya dace da IR Spectrum na AG RS |
Gano UV | A cikin 259nm da 332nm wurin tsayin raƙuman ruwa yakamata su sami matsakaicin sha |
Ruwa | 2.5-4.5% |
Magani Launi & Tsafta | Ya kamata Magani ya zama Bayyanar Launi |
Alaka Abubuwan | |
Najasa A + Najasa H | ≤0.10% |
Rashin tsarki B | ≤0.10% |
Najasa C + Najasa E | ≤0.10% |
Rashin tsarki D | ≤0.10% |
Rashin tsarki I | ≤0.10% |
Bach na rashin Tsaftar da ba a bayyana ba | ≤0.10% |
Jimlar ƙazanta | ≤0.30% |
Ragowar Magani | |
Methanol | ≤3000ppm |
Ethanol | ≤5000ppm |
Dichloromethane | ≤600ppm |
Ethyl acetate | ≤5000ppm |
Enantiomer (HPLC) | ≤0.10% |
Isomer Ratio (HPLC) | 30.0% -40.0% |
Chloride | ≤0.01% |
Ragowa akan Ignition | ≤0.10% |
Karfe masu nauyi | ≤10ppm |
Bacterial Endotoxins | <5EU/mg |
Iyakar Microbial | TAMC ≤1000 cfu/g |
Assay | 98.0% -102.0% (a kan anhydrous tushen) |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | API, Wakilin Antithrombotic na roba Anticoagulant |
Kunshin: Bottle, Aluminum tsare jakar, Kwali Drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta kuma mai ba da kayayyaki na Argatroban (CAS: 74863-84-6) tare da babban inganci, API.
Argatroban (CAS: 74863-84-6) wani sabon roba antithrombotic wakili da amfani a kiyaye anticoagulation su ischemic bugun jini da kuma yada intravascular coagulation.Yana da maganin ƙwanƙwasawa wanda shine ƙaramin ƙwayar ƙwayar ƙwayar cuta kai tsaye mai hana thrombin.A cikin 2000, Cibiyar Abinci da Magunguna (FDA) ta ba da lasisin argatroban don rigakafi ko maganin thrombosis a cikin marasa lafiya tare da thrombocytopenia mai haifar da heparin (HIT).A cikin 2002, an ba da izinin amfani da shi a yayin da ake aiwatar da aikin jijiyoyin jini a cikin marasa lafiya waɗanda ke da HIT ko kuma suna cikin haɗarin haɓaka ta.A cikin 2012, MHRA ta amince da ita a cikin Burtaniya don maganin rigakafi a cikin marasa lafiya tare da heparin-induced thrombocytopenia Type II (HIT) wanda ke buƙatar magungunan antithrombotic parenteral.