Aripiprazole CAS 129722-12-9 Tsafta > 99.0% (HPLC) API
Maƙerin Samar da Matsakaici na Aripiprazole Tare da Tsabta Mai Girma
Aripiprazole API CAS 129722-12-9
1- (2,3-Dichlorophenyl) Piperazine Hydrochloride CAS 119532-26-2
7-Hydroxy-3,4-Dihydro-2(1H) -Quinolinone CAS 22246-18-0
7- (4-Bromobutoxy) -3,4-Dihydro-2(1H) -Quinolinone CAS 129722-34-5
| Sunan Sinadari | Aripiprazole |
| Makamantu | 7-[4-[4- (2,3-Dichlorophenyl) -1-Piperazinyl] butoxy] -3,4-Dihydro-2 (1H) -Quinolinone |
| Lambar CAS | 129722-12-9 |
| Lambar CAT | Saukewa: RF-PI2270 |
| Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
| Tsarin kwayoyin halitta | Saukewa: C23H27Cl2N3O2 |
| Nauyin Kwayoyin Halitta | 448.39 |
| Solubility | Mai Soluble A Ruwa;Insoluble a cikin methanol |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Fari ko Kusan Farin Crystalline Foda |
| Ganewa | ta IR;Farashin HPLC |
| Solubility | Mai narkewa a cikin Acetic Acid, Dan Soluble a cikin Ethanol |
| Matsayin narkewa | 136.0 ~ 140.0 ℃ |
| Asara akan bushewa | <0.50% |
| Ragowa akan Ignition | <0.10% |
| Karfe masu nauyi | ≤20ppm |
| Ragowar Magani | |
| Ethanol | ≤1000ppm |
| DMF | ≤200ppm |
| Abubuwa masu alaƙa | |
| Duk Wani Rashin Tsabtace Guda Daya | <0.20% |
| Jimlar ƙazanta | <1.00% |
| Tsarkake / Hanyar Bincike | > 99.0% (HPLC) |
| Assay | 98.0% ~ 102.0% (akan Anhydrous Basis) |
| Ƙananan Iyakoki | |
| Jimlar Ƙididdigar Ƙwayoyin Ƙirar Ƙira | ≤1000 cfu/g |
| Yisti da Mold Haɗe | ≤100 cfu/g |
| E·Coli | Babu |
| Shirye-shiryen pathogenic | Babu |
| Matsayin Gwaji | Matsayin Kasuwanci |
| Amfani | API;Antipsychotic |
Kunshin: kwalban, 5kg / Aluminum tin, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
Aripiprazole (CAS: 129722-12-9) wani sabon nau'i ne na abubuwan da suka samo asali na quinoline mai narkewa sosai, halayensa na pharmacological shine cewa ba wai kawai postsynaptic dopamine D2 antagonist bane, har ma da presynaptic dopamine D2 agonist mai karɓa, yana iya kuma burge D1, D3, D4 masu karɓa.Aripiprazole shine ƙarni na biyu atypical antipsychotic da anti-depressant tare da wani ɓangare na agonist aiki a dopamine D2 da serotonin 5-HT1A masu karɓa da kuma antagonist aiki a serotonin 5-HT2A masu karɓa.Kimar Ki sune 0.34 nM, 0.8 nM, 1.7 nM, da 3.4 nM, bi da bi, don dopamine D2 da D3, serotonin 5-HT1A da 5-HT2A masu karɓa.Ana amfani da Aripiprazole don maganin schizophrenia da cututtukan kwakwalwa masu alaƙa.Bristol-Myers Squibb da Otsuka Pharmaceutical Company sun sanar da cewa Tarayyar Turai ta amince da Abilify (Aripiprazole) a cikin maganin lissafin schizophrenia.Schizophrenia yana shafar kashi 1% na yawan al'ummar duniya, da ƙari a cikin matasa.Schizophrenia yana rinjayar tunani, sarrafa motsin rai da ikon yanke shawara na majiyyaci.Magungunan schizophrenia-tabbatacce za su sami alamun bayyanar cututtuka irin su hallucinations da ruɗi, marasa lafiya tare da mummunan bayyanar cututtuka sune janyewar zamantakewa, rashin canje-canje na tunani.A cikin 2002 FDA ta amince da Abilify don maganin schizophrenia, wanda yana da ƙarfin sashi biyar: 5 MG, 10 MG, 15 MG, 20 MG da 30 MG, tun lokacin amincewarsa.
