Atazanavir CAS 198904-31-3 Tsarkake ≥99.0% API Factory Anti-HIV HIV-1 Protease Inhibitor

Atazanavir (CAS 198904-31-3) antiretroviral ne, labari kuma mai karfin maganin azapeptide na ajin protease inhibitor (PI).Ana sayar da shi a ƙarƙashin sunan kasuwanci Reyataz.Kamar sauran antiretrovirals, ana amfani da shi don magance kamuwa da cuta na nau'in rigakafi na ɗan adam nau'in 1 (HIV-1) protease enzyme tare da hanawa akai-akai Ki na 66 nmol/L kuma yana hana kwafin kwayar cutar HIV-1 tare da 50% ingantaccen maida hankali EC50 kama daga 2.6 zuwa 5.3 nmol/L.Atazanavir yana ɗaure da kwayar cutar HIV-1 yana hana ɓarna gag da gag-pol polyproteins, wanda ke haifar da samuwar virions marasa girma a cikin ƙwayoyin cutar HIV-1.Atazanavir yana da nau'in sinadarai na sinadarai na C-2 daban-daban kuma gabaɗaya mafi girman ƙarfin rigakafin cutar HIV a cikin nau'ikan HIV daban-daban idan aka kwatanta da sauran masu hana protease, gami da Indinavir, Nelfinavir, Ritonavir, Saquinavir da Amprenavir.An bambanta Atazanavir daga sauran PIs a cikin cewa ana iya ba da shi sau ɗaya a rana kuma yana da ƙananan tasiri akan bayanan lipid na mai haƙuri.Kamar sauran masu hana protease, ana amfani dashi kawai tare da sauran magungunan HIV.Atazanavir novel azapeptide HIV protease inhibitor.Antiviral.Ana shan ta baki sau ɗaya a rana.