Atazanavir Sulfate CAS 229975-97-7 Tsarkakewa ≥99.0% API Factory Anti-HIV HIV-1 Protease Inhibitor

Atazanavir Sulfate (BMS-232632 Sulfate) (CAS: 229975-97-7) wani nau'i ne na gishiri sulfate na atazanavir wanda ke da zaɓin mai hana cutar HIV-1 mai hanawa, shine mai hanawa na farko da aka amince da shi don gudanarwa na yau da kullum.Atazanavir Sulfate shine mai hanawa kuma mai hanawa na CYP3A4, kuma mai hanawa da inducer na P-glycoprotein (P-gp).Atazanavir Sulfate kuma shine mai hana SARS-CoV 3CLpro tare da IC50 na 3.49 μM.Atazanavir Sulfate ne azapeptide da HIV-protease inhibitor da aka yi amfani da magani daga HIV cututtuka da AIDS a hade tare da sauran Anti-HIV Agents, an ɓullo da kuma kaddamar da Bristol-Myers Squibb (BMS), a karkashin duniya lasisi daga Novartis. don maganin cutar HIV.An ƙaddamar da Atazanavir a Amurka azaman Reyataz™ a cikin Yuli 2003. Antiviral.Atazanavir ya nuna gabaɗaya ya fi ƙarfi fiye da biyar da aka amince da su a halin yanzu masu hana cutar HIV-1.Atazanavir yana hana ƙwayar ƙwayar cuta ta musamman na Gag da Gag-Pol polyproteins a cikin kwayoyin cutar HIV-1 ta hanyar ɗaure wurin aiki na kwayar cutar HIV-1, don haka hana samuwar virions balagagge.Atazanavir baya aiki akan HIV-2.