Bicalutamide CAS 90357-06-5 API Factory High Quality Advanced Prostate Cancer

Takaitaccen Bayani:

Suna: Bicalutamide

Saukewa: 90357-06-5

Bayyanar: Fari zuwa Kashe-Farin Crystalline Foda

Matsayi: 98.0% ~ 102.0%

Bicalutamide a cikin maganin Ciwon daji na Prostate Ci gaba

API High Quality, Kasuwancin Kasuwanci

Inquiry: alvin@ruifuchem.com

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Bayani:

Samar da Mai ƙira tare da Tsaftataccen Tsafta da Tsayayyen inganci
Suna: Bicalutamide
Saukewa: 90357-06-5
Bicalutamide a cikin maganin Ciwon daji na Prostate Ci gaba
API High Quality, Kasuwancin Kasuwanci

Abubuwan Sinadarai:

Suna	Bicalutamide
Makamantu	N-[4-Cyano-3- (trifluoromethyl) phenyl] -3-[(4-fluorophenyl) sulfonyl] -2-hydroxy-2-methylpropionamide
Lambar CAS	90357-06-5
Lambar CAT	RF-API76
Matsayin Hannun jari	A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram
Tsarin kwayoyin halitta	Saukewa: C18H14F4N2O4S
Nauyin Kwayoyin Halitta	430.37
Ajiya Zazzabi	2-8 ℃
Alamar	Ruifu Chemical

Ƙayyadaddun bayanai:

Abu	Ƙayyadaddun bayanai
Bayyanar	Fari zuwa Kashe-White Crystalline Foda
Identification A	IR: Bakan samfurin yayi daidai da na ma'aunin tunani
Identity B	HPLC: Lokacin riƙewa na babban kololuwar samfurin samfurin ya dace da na daidaitaccen bayani
Gano C	Fahimtar Halitta Fluoride
Solubility	Mai Soluble Kyauta a Acetone da Tetrahydrofuran, Dan Soluble a cikin Ethyl Acetate
Matsayin narkewa	191.0 ~ 195.0 ℃
Abubuwan Ruwa (na KF)	≤0.20%
Abun ciki na Fluoride	15.9% ~ 18.5%
Asara akan bushewa	≤0.50%
Ragowa akan Ignition	≤0.10%
Karfe masu nauyi	≤10ppm
Ragowar Magani
Tetrahydrofuran	≤0.072%
Toluene	≤0.089%
N-Hexane	≤0.029%
Acetone	≤0.50%
Ethyl acetate	≤0.50%
Abubuwa masu alaƙa
N, N'-Dimethyl Acetamide	≤0.109%
Bicalutamide Aminobenzonitrile	≤0.10%
Abubuwan da ke da alaƙa da Bicalutamide A Isomer A	≤0.10%
Abubuwan da ke da alaƙa da Bicalutamide A Isomer B	≤0.10%
Desfluoro Bicalutamide	≤0.20%
2-Fluoro Bicalutamide	≤0.20%
Deoxy Bicalutamide	≤0.20%
Bicalutamide Sulfide	≤0.10%
Duk Wani Tsaftar Da Ba A Fayyace Ba	≤0.10%
Jimlar ƙazanta	≤0.50%
Girman Barbashi	90% <10um;50% <5um
Assay	98.0% ~ 102.0% (a kan busassun tushe)
Gwajin Kwayoyin Halitta
Jimlar Ƙididdigar Aerobic Mai Mahimmanci	≤500CFU/g
Yisti da Molds	≤50CFU/g
Rayuwar Rayuwa	Watanni 24
Matsayin Gwaji	Matsayin Kasuwanci;USP Standard
Amfani	API, a cikin maganin Ciwon Ciwon Ciwon Jiki na Prostate

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.

Amfani:

FAQ:

Aikace-aikace:

Bicalutamide (CAS: 90357-06-5) wani antagonist ne wanda ba steroidal androgen antagonist, wanda ke gasa mai karɓar mai karɓa na androgen tare da androgen, yana toshe ɗaukar kwayar halitta na androgen, kuma yana hana ɗaurin androgens zuwa gaɓar manufa.Yana ɗaure tare da mai karɓa na androgen wanda ke samar da hadaddun mai karɓa, wanda ke shiga tsakiya kuma ya haɗa tare da nucleoprotein, saboda haka yana hana haɓakar ƙwayoyin tumor.Zai iya zama azaman magani na farko don maganin ciwon daji na prostate mai ci gaba.An ƙaddamar da Bicalutamide a cikin Ƙasar Ingila, kasuwarsa ta farko a duniya, don maganin ciwon daji na prostate mai ci gaba a hade tare da analog na LHRH ko simintin tiyata.Wani antiandrogen wanda ba na steroidal ba, mai zaɓi na gefe, bicalutamide yana hana aikin dihydrotestosterone da testosterone a wuraren da aka yi niyya ta hanyar haɗin kai ga mai karɓar androgen cytosolic.An ba da rahoton cewa an jure shi da kyau ba tare da wani tasiri mai mahimmanci na cututtukan zuciya da na rayuwa ba saboda amfanin rashin kowane aikin steroid.An nuna ingancin bicalutamide a matsayin monotherapy a asibiti.An kuma bayar da rahoton adadin martani mai ban sha'awa a cikin kula da launin fata, nono, pancreas da kuma cututtukan huhu marasa kanana.