Brexpiprazole CAS 913611-97-9 Tsarkake>99.0% (HPLC) Kamfanin API
Ruifu Chemical Supply Brexpiprazole Intermediates
Brexpiprazole CAS 913611-97-9
7-Hydroxyquinolinone CAS 70500-72-0
4-Bromobenzo [b] thiophene CAS 5118-13-8
1- (1-Benzothiophen-4-yl) Piperazine Hydrochloride CAS 913614-18-3
7- (4-Chlorobutoxy) quinolin-2(1H) -daya CAS 913613-82-8
4-Chlorobenzo [b] thiophene CAS 66490-33-3
Sunan Sinadari | Brexpiprazole |
Makamantu | OPC-34712;7- (4- (4- (Benzo [b]thiophen-4-yl)piperazin-1-yl)butoxy) quinolin-2 (1H) -daya |
Lambar CAS | 913611-97-9 |
Lambar CAT | RF-PI1982 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C25H27N3O2S |
Nauyin Kwayoyin Halitta | 433.57 |
Yawan yawa | 1.245± 0.060 g/cm3 |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari ko Kashe-White Crystalline Foda |
Ganewa | By IR |
RT | A karkashin chirality ya kamata a bi |
Chloride | Yana ba da amsawar chloride |
Ruwa | 3.0% ~ 4.5% |
Matsayin narkewa | 198.0 ~ 202.0 ℃ |
Ragowa akan Ignition | <0.20% |
Karfe masu nauyi | ≤10ppm |
Abubuwa masu alaƙa | |
Rashin Tsabtace Mutum | <0.50% |
Jimlar ƙazanta | <1.00% |
EE | >99.0% |
Tsarkake / Hanyar Bincike | > 99.0% (HPLC, akan busassun tushe) |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | API |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
Brexpiprazole (CAS: 913611-97-9) ɗan takarar magani ne mai amfani a cikin jiyya da rigakafin rikice-rikicen tunani ciki har da cututtukan CNS.Brexpiprazole wani sabon magani ne na antipsychotic wanda ke aiki azaman mai sarrafa ayyukan serotonin ® dopamine kuma ya nuna inganci azaman jiyya na haɗin gwiwa a cikin marasa lafiya tare da babban rashin damuwa (MDD).Brexpiprazole yana nuna bayanin martaba na musamman na likitanci, yana aiki azaman agonist na yanki na serotonin 5-HT1A da dopamine D2 masu karɓa kuma a matsayin cikakken antagonist na 5-HT2A da noradrenaline α1B/2C masu karɓa, tare da alaƙar ɗaurin subnanomolar iri ɗaya.Brexpiprazole Otsuka da Lundbeck ne suka haɓaka, an amince da su a cikin 2015 ta FDA don maganin schizophrenia kuma a matsayin ƙarin magani don damuwa.An yi la'akari da Brexpiprazole a matsayin magajin Otsuka's antipsychotic miyagun ƙwayoyi aripiprazole (sunan ciniki Abilify) wanda ikon mallaka ya ƙare a watan Agusta 2014.