Brigatinib CAS 1197953-54-0 Tsaftace>99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta na Brigatinib (AP-26113) (CAS: 1197953-54-0) tare da babban inganci.Ruifu Chemical na iya samar da isar da saƙo na duniya, farashi mai gasa, kyakkyawan sabis, ƙanana da adadi mai yawa akwai.Sayi Brigatinib,Please contact: alvin@ruifuchem.com
Sunan Sinadari | Brigatinib |
Makamantu | AP26113;AP-26113;5-Chloro-N4-[2- (Dimethylphosphinyl) phenyl] -N2-[2-Methoxy-4-[4- (4-Methyl-1-Piperazinyl) -1-Piperidinyl] phenyl] -2,4-Pyrimidinediamine |
Matsayin Hannun jari | A Stock, Kasuwancin Kasuwanci |
Lambar CAS | 1197953-54-0 |
Tsarin kwayoyin halitta | Saukewa: C29H39ClN7O2P |
Nauyin Kwayoyin Halitta | 584.09 g/mol |
Matsayin narkewa | > 203 ℃ (Dec.) |
Yawan yawa | 1.31± 0.10 g/cm3 |
COA & MSDS | Akwai |
Asalin | Shanghai, China |
Alamar | Ruifu Chemical |
Abubuwa | Ƙayyadaddun bayanai | Sakamako |
Bayyanar | Fari zuwa Kashe-Farin Foda | Ya bi |
Tsarkake / Hanyar Bincike | > 99.0% (HPLC) | 99.26% |
Max.Tsaftace Guda Daya | <1.00% | 0.25% |
Asara akan bushewa | <1.00% | 0.27% |
Infrared Spectrum | Daidai da Tsarin | Ya bi |
1H NMR Spectrum | Daidai da Tsarin | Ya bi |
Kammalawa | An gwada samfurin kuma ya dace da ƙayyadaddun da aka bayar |
Kunshin:Fluorinated Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye akwati sosai kuma a adana a cikin sanyi, busasshe kuma mai cike da iska daga abubuwan da ba su dace ba.Kare daga haske da danshi.
Jirgin ruwa:Isar da shi zuwa duniya ta iska, ta FedEx / DHL Express.Bayar da isarwa cikin sauri kuma abin dogaro.
Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.
Manyan Kasuwanni?Sayarwa zuwa kasuwannin cikin gida, Arewacin Amurka, Turai, Indiya, Koriya, Jafananci, Australia, da sauransu.
Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.
inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.
Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.
MOQ?Babu MOQ.Karamin tsari abin karɓa ne.
Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.
Sufuri?By Express (FedEx, DHL), ta Air, ta Teku.
Takardu?Bayan sabis na tallace-tallace: COA, MOA, ROS, MSDS, da dai sauransu za a iya ba da su.
Haɗin Kan Al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.
Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.
Brigatinib (AP-26113) (CAS: 1197953-54-0) wani bincike ne na ƙananan ƙwayoyin cuta da ake nufi da ciwon daji wanda ARIAD Pharmaceuticals, Inc. Anaplastic lymphoma kinase (ALK).Brigatinib wani zaɓi ne na agonist akan bambancin EGFR sabanin nau'ikan mutant na daji.Har ila yau, miyagun ƙwayoyi yana kwatanta zaɓe a kan al'amuran haɗin gwiwar ALK-EML4, wanda shine muhimmin al'amari na gyaggyarawa na ɓarna na huhu mai sauƙi.An wajabta Brigatinib ga marasa lafiya tare da takamaiman kwayoyin halitta marasa kyau da kuma lokacin da cutar kansar huhu mara ƙaranci (NSCLC) ba ta da amsa ga gudanarwa tare da wasu magunguna.An rarraba Brigatinib a matsayin mai hana kinase, wanda tsarin aikinsa ya haɗa da murkushe ayyukan sunadarai marasa kyau waɗanda ke haɓaka haɓakar ƙwayoyin cutar kansa.
An wajabta Brigatinib (CAS: 1197953-54-0) ga marasa lafiya da ke da takamaiman nau'ikan NSCLC waɗanda suka yadu zuwa sassa daban-daban na jiki a cikin mutanen da suka sha maganin da suka gabata tare da wasu magungunan ciwon daji kamar Crizotinib, kuma yanayinsu ya yi muni. ko kuma suna nuna ƙananan alamun ingantawa.Ana gudanar da bincike ne musamman don ingancin maganin cutar kansar huhun mara kanana (NSCLC) inda aka kunna ALK kuma maye gurbin EGFP akai-akai yana faruwa.
Brigatinib (AP-26113) (CAS: 1197953-54-0) sabon mai hanawa ne na tyrosine kinase, yana nuna tasiri mai mahimmanci a cikin ALK + metastatic NSCLC.A ranar 30 ga Agusta, 2016, FDA ta Amurka ta ba da bugtinib a matsayin maganin ci gaba da ƙwayar cuta mai wuya ga ALK + NSCLC a cikin marasa lafiya waɗanda suka haɓaka ko ba za su iya jure wa Crizotinib ba, maganin ALK + NSCLC na ƙarni na farko.Ba da fifiko ga bitar aikace-aikacen jeri kuma ba da damar ƙaddamar da bayanan aikace-aikacen akan tsarin birgima.FDA ta amince da Bugtinib a ranar 28 ga Afrilu, 2017, a ƙarƙashin sunan kasuwanci Aunbrigtm.