N,O-Bis(trimethylsilyl)trifluoroacetamide (BSTFA) CAS 25561-30-2 99% BSTFA + 1% TMCS na GC Factory

N, O-Bis (trimethylsilyl) trifluoroacetamide (BSTFA) (CAS: 25561-30-2) ana amfani da shi don haɗakar magungunan magunguna.Ana amfani dashi azaman mai amsawa a cikin shirye-shiryen pyrimidinone ribosides da analogs waɗanda ke nuna kaddarorin anti-tumo.BSTFA tare da trimethylchlorosilane ya samo aikace-aikacen da za a yi amfani da shi a cikin chromatography gas (GC) da mass-spectrometry (MS).BSTFA yayi kama da BSA a cikin ƙayyadaddun gyare-gyare kuma akwai binciken da yawa waɗanda suka yi amfani da reagents biyu.Ɗaya daga cikin binciken ya gano BSTFA ya fi BSA a cikin kwanciyar hankali na samfur da yawan amfanin ƙasa.Wani binciken ya kwatanta masu ba da gudummawar trimethylsilyl da yawa don ƙarshen silica kuma ya lura cewa BSTFA ya fi BSA aiki amma ƙasa da amsawa fiye da TMCim.Dukansu BSA da BSTFA an yi amfani da su don shirya abubuwan da suka samo asali na trimethylsilyl na pyrimidine da purines.Ana amfani da BSTFA don dalilai na nazari ko azaman sinadarai reagent don haɓakar ƙwayoyin ƙwayoyin cuta masu rikitarwa.Yana da silylation reagent mai amfani a cikin GC da GC-MS don rarrabuwar ƙungiyoyin ayyuka da yawa a ƙarƙashin yanayi mara kyau.BSTFA shine matsakaicin magunguna mai mahimmanci, wanda zai iya rage polarity na abubuwan da ke dauke da hydroxy da kuma kara yawan karfin su, yin samfurori mafi dacewa don nazarin GC.A matsayin m tsaka tsaki silanylation reagent, shi ba kawai yana da high reactivity, mai kyau selectivity, amma kuma yana da abũbuwan amfãni daga high dauki yawan amfanin ƙasa da kuma sauki post-jiyya.Hakanan ana amfani dashi azaman mai hanawa DAT da mai hana SLC6A2.Ana amfani da shi akai-akai don ƙaddamar da acid carboxylic, phenols, steroids, amines, alcohols, da alkaloids da amides.