Candesartan Cilexetil CAS 145040-37-5 Tsarkake> 99.0% (HPLC) API Factory Feature Image

Candesartan Cilexetil CAS 145040-37-5 Tsarkake>99.0% (HPLC) Kamfanin API

Takaitaccen Bayani:

Sunan Chemical: Candesartan Cilexetil

Saukewa: 145040-37-5

Tsafta:> 99.0% (HPLC)

Bayyanar: Fari zuwa Kashe-Farin Crystalline Foda

Zaɓaɓɓen Angiotensin II Mai karɓar Mai karɓa

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E-Mail: alvin@ruifuchem.com

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Bayani:

Ruifu Chemical Supply Candesartan Cilexetil Matsakaici Tare da Babban Tsafta
Candesartan Cilexetil CAS 145040-37-5
Candesartan CAS 139481-59-7
1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83-2
Candesartan Cilexetil Intermediate Eethyl Ester C6 CAS 139481-41-7
Candesartan Cilexetil Matsakaici CAS 139481-44-0
Tril Candesartan Cilexetil CAS 170791-09-0

Abubuwan Sinadarai:

Sunan Sinadari	Candesartan Cilexetil
Makamantu	TCV-116;1- ((((Cyclohexyloxy) carbonyl) oxy) ethyl 1- ((2'- (1H-tetrazol-5-yl)-[1,1'-biphenyl] -4-yl) methyl) -2-ethoxy-1H -benzo[d] imidazole-7-Carboxylate
Lambar CAS	145040-37-5
Lambar CAT	Saukewa: RF-PI1891
Matsayin Hannun jari	A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton
Tsarin kwayoyin halitta	Saukewa: C33H34N6O6
Nauyin Kwayoyin Halitta	610.66
Alamar	Ruifu Chemical

Ƙayyadaddun bayanai:

Abu	Ƙayyadaddun bayanai
Bayyanar	Fari zuwa Kashe-White Crystalline Foda
Bayanin HPLC	Lokacin riƙewa na babban kololuwa a cikin chromatogram na samfurin ya dace da wanda ke cikin chromatogram da aka samu tare da ma'auni.
Gano IR	IR infrared absorption spectrum yayi daidai da na Candesartan Cilexetil.
Tsallakewa da Maganin Launi	Magani a cikin chloroform a 5% bayyananne kuma mara launi
Tsarkake / Hanyar Bincike	> 99.0% (HPLC)
Matsayin narkewa	155.0 ~ 160.0 ℃
Asara akan bushewa	<0.30%
Ragowa akan Ignition	<0.10%
Karfe masu nauyi	<10ppm
Arsenic (AS)	<1ppm
Rarraba Girman Barbashi	90% <30 μm
Najasa Na Halitta	ta HPLC
Ethyl Candesartan	<0.15%
Desetyl Candesartan	<0.15%
N2-Ethyl Candesartan Cilexei	<0.15%
Duk wani rashin tsarkin da ba a sani ba	<0.15%
Jimlar ƙazanta	<0.60%
Binciken Potentiometry	99.0 ~ 101.0% na C33H34N6O6, an ƙididdige shi akan abu mai anhydrous
Halin Halin Halin Halitta
Methano	<0.30%
Ethanol	<0.50%
Diethyl Ether	<0.50%
Aceton	<0.50%
Dichloromethan	<0.06%
Dimethylformamide	<0.088%
Kwayoyin Halitta
Jimlar Ƙididdigar Ƙwayoyin Ƙirar Ƙira	<1000cfu/g
Molds & Yeasts	<100cfu/g
E.Coli	Babu
Salmonella	Babu
Matsayin Gwaji	Matsayin Kasuwanci
Amfani	API;Wakilin antihypertensive

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi

Amfani:

FAQ:

Aikace-aikace:

Candesartan Cilexetil (TCV-116) (CAS: 145040-37-5) wani antagonist mai karɓa na angiotensin II tare da IC50 na 0.26 nM, wanda aka yi amfani da shi wajen maganin hauhawar jini.Candesartan shine mai hana masu karɓa na angiotensin (ARB) wanda za'a iya amfani dashi shi kaɗai ko tare da wasu wakilai don magance hauhawar jini.Ana gudanar da shi ta baki a matsayin prodrug, candesartan cilexetil, wanda ke canzawa da sauri zuwa metabolite mai aiki, candesartan, yayin sha a cikin sashin gastrointestinal.Candesartan yana rage karfin jini ta hanyar haɓaka tsarin renin-angiotensin-aldosterone (RAAS);yana gasa tare da angiotensin II don ɗaure nau'in-1 angiotensin II mai karɓa (AT1) subtype kuma yana hana haɓakar hawan jini na angiotensin II.Ba kamar angiotensin-converting enzyme (ACE) masu hanawa, ARBs ba su da mummunan tasirin tari mai bushe.Ana iya amfani da Candesartan don magance hauhawar jini, keɓewar hauhawar jini na systolic, hypertrophy na ventricular hagu da ciwon sukari nephropathy.Hakanan za'a iya amfani dashi azaman madadin wakili don maganin cututtukan zuciya, rashin aiki na systolic, ciwon zuciya na zuciya da cututtukan jijiyoyin jini.