Daclatasvir Dihydrochloride Matsakaici CAS 1007882-23-6 Tsarkake>98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. shine babban kamfani na Daclatasvir Dihydrochloride Intermediate (CAS: 1007882-23-6) tare da babban inganci.Ruifu Chemical na iya samar da isar da sako na duniya, farashi mai gasa, ƙanana da yawa da ake samu.Sayi Daclatasvir Dihydrochloride Intermediates,Please contact: alvin@ruifuchem.com
| Sunan Sinadari | Di-tert-Butyl (2S,2'S) -2,2'-(4,4'-Biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-Pyrrolidinecarboxylate) |
| Makamantu | Daclatasvir Matsakaici Ⅱ;Dacaltasvir Matsakaici 02;Daclatasvir T-Butyl Ester;Bis (2-Methyl-2-Propanyl) (2S,2'S) -2,2'- [4,4'-Biphenyldiylbis (1H-Imidazole-4,2-diyl)] di (1-Pyrrolidinecarboxylate);Di-tert-butyl 2,2'-([1,1'-Biphenyl] -4,4'-diylbis(1H-Imidazole-5,2-diyl))(2S,2'S)-bis(Pyridineidine-1- Carboxylate;(2S,2'S)-2,2'-([1,1'-Biphenyl]-4,4'-diyldi-1H-Imidazole-5,2-diyl)bis-1-Pyrrolidinecarboxylic Acid 1,1'-Bis (1,1-Dimethylethyl) Ester;Daclatasvir rashin tsarki 4 |
| Matsayin Hannun jari | A Stock, Kasuwancin Kasuwanci |
| Lambar CAS | 1007882-23-6 |
| Tsarin kwayoyin halitta | Saukewa: C40H51ClN8O6 |
| Nauyin Kwayoyin Halitta | 775.35 g/mol |
| Wurin Tafasa | 890.2± 65.0 ℃ a 760 mmHg |
| Yawan yawa | 1.220± 0.06 g/cm3 |
| COA & MSDS | Akwai |
| Asalin | Shanghai, China |
| Kashi | Matsakaicin Daclatasvir Dihydrochloride (CAS: 1009119-65-6) |
| Alamar | Ruifu Chemical |
| Abubuwa | Ƙayyadaddun bayanai | Sakamako |
| Bayyanar | Rawaya Mai Haske zuwa Foda Rawaya | Hasken Rawaya Foda |
| Asara akan bushewa | <1.00% | 0.65% |
| Matsakaicin Tsabtace Guda Daya | <1.00% | 0.45% |
| Jimlar ƙazanta | <2.00% | 1.24% |
| Tsarkake / Hanyar Bincike | 98.0% (HPLC) | 98.76% |
| Infrared Spectrum | Daidai da Tsarin | Ya bi |
| 1H NMR Spectrum | Daidai da Tsarin | Ya bi |
| Kammalawa | An gwada samfurin kuma ya dace da ƙayyadaddun da aka bayar | |
| Aikace-aikace | Matsakaicin Daclatasvir Dihydrochloride (CAS: 1009119-65-6) | |
Kunshin:Fluorinated Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
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Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.
Manyan Kasuwanni?Sayarwa zuwa kasuwannin cikin gida, Arewacin Amurka, Turai, Indiya, Koriya, Jafananci, Australia, da sauransu.
Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.
inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.
Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.
MOQ?Babu MOQ.Karamin tsari abin karɓa ne.
Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.
Sufuri?By Express (FedEx, DHL), ta Air, ta Teku.
Takardu?Bayan sabis na tallace-tallace: COA, MOA, ROS, MSDS, da dai sauransu za a iya ba da su.
Tsarin al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.
Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.
Di-tert-Butyl (2S,2'S) -2,2'-(4,4'-Biphenyldiylbis(1H-imidazole-5,2-diyl))di (1-Pyrrolidinecarboxylate) (CAS: 1007882-23-6) shi ne matsakaicin Daclatasvir Dihydrochloride (CAS: 1009119-65-6).
Daclatasvir (Daklinza) ya sami matsayi na "priority review", hade da Sorafenib don kula da genotype III manya marasa lafiya da ciwon hanta na kullum C. Daklinza ya kasance na farko da miyagun ƙwayoyi da aka tabbatar da cewa yana da tasiri a cikin maganin genotype III hepatitis C. kamuwa da cuta ba tare da haɗin gwiwa tare da interferon ko ribavirin ba.Interferon da Ribavirin kwayoyi ne guda biyu da FDA ta amince da su don maganin kamuwa da cutar hanta.Hepatitis C cuta ce da ke haifar da kumburin hanta, wanda ke haifar da raguwar aikin hanta ko gazawar hanta.Yawancin marasa lafiya da suka kamu da cutar hanta ba su da alamun cutar har sai lalacewar hanta ta bayyana, wanda zai iya ɗaukar shekaru da yawa.A duniya baki daya, genotype III Hepatitis C shi ne na biyu mafi yawan kwayoyin cutar hanta ta hanta bayan genotype 1 hepatitis C kuma ana daukarsa a matsayin daya daga cikin cututtuka na genotype.Daklinza shine pan-genotype NS5A mai hanawa mai rikitarwa, tare da ingancin hana kwafin RNA da taron hoto na hoto, tasirin antiviral dual.Don nazarin in vitro, an nuna Daklinza yana da tasirin anti-viral akan kwayar cutar hanta ta 1 ~ 6.Daklinza yana tare da gargaɗin cewa haɗuwa da amiodarone, Daklinza da Sofosbuvir na iya haifar da raguwar bugun zuciya mai tsanani.Daklinza kwamfutar hannu ce ta baka tare da shawarar kashi na 60 MG na sau 1/d, tare da Sofosbuvir na tsawon makonni 12.
Kamfanin bincike da ci gaba: Bristol-Myers Squibb.
Littattafan Haɓaka: WO 2008021927A2 (Agusta 9, 2007).
Lokacin tallace-tallace: Yuli 24, 2015 da aka jera a Amurka, sunan kasuwanci Daklinza.
Alamomi: Ana amfani da su a hade tare da Sofosbuvir don maganin ciwon hanta na 3 na kullum na genotype 3 (HCV).
Tsarin aiki: HCV furotin mara tsari 5A (NS5A) masu hanawa.Mummunan halayen: ciwon kai da gajiya.
Formulation da ƙayyadaddun bayanai: Allunan, 30 da 60mg.
