4-Amino-5-Chloro-2,3-Dihydrobenzofuran-7-Carboxylic Acid CAS 123654-26-2 Prucalopride Succinate Tsarkake Tsarkakewa ≥98.0% (HPLC)
Shanghai Ruifu Chemical shine babban masana'anta na 4-Amino-5-Chloro-2,3-Dihydrobenzofuran-7-Carboxylic Acid (CAS: 123654-26-2) tare da babban inganci.Ruifu Chemical na iya samar da isar da saƙo na duniya, farashi mai gasa, kyakkyawan sabis, ƙanana da adadi mai yawa akwai.Sayi Prucalopride Succinate Intermediates,Please contact: alvin@ruifuchem.com
| Sunan Sinadari | 4-Amino-5-Chloro-2,3-Dihydrobenzofuran-7-Carboxylic Acid |
| Makamantu | 4-Amino-5-Chlorocoumaran-7-Carboxylic Acid;4-Amino-5-Chloro-2,3-Dihydrobenzo[b]furan-7-Carboxylic Acid;4-Amino-5-Chloro-2,3-Dihydro-1-Benzofuran-7-Carboxylic Acid;4-Amino-5-Chloro-2,3-Dihydro-7-Benzofurancarboxylic Acid;Prucalopride rashin tsarki A;Prucalopride Succinate rashin tsarki-2 |
| Matsayin Hannun jari | A Stock, Kasuwancin Kasuwanci |
| Lambar CAS | 123654-26-2 |
| Tsarin kwayoyin halitta | Saukewa: C9H8ClNO3 |
| Nauyin Kwayoyin Halitta | 213.62 g/mol |
| Matsayin narkewa | 242 ℃ (Dec.) |
| Wurin Tafasa | 406.5 ± 45.0 ℃ |
| Yawan yawa | 1.566 |
| COA & MSDS | Akwai |
| Asalin | Shanghai, China |
| Kashi | Matsakaicin Prucalopride Succinate (CAS: 179474-85-2) |
| Alamar | Ruifu Chemical |
| Abubuwa | Ka'idojin dubawa | Sakamako |
| Bayyanar | Kashe-Fara zuwa Haske-Ja Mai ƙarfi | Haske-Ja Mai ƙarfi |
| Ruwa ta Karl Fischer | ≤1.00% | 0.35% |
| Ragowa akan Ignition | <0.20% | 0.08% |
| Karfe masu nauyi (Pb) | ≤20ppm | <10ppm |
| Tsaftace Guda Daya | ≤1.00% | Ya bi |
| Jimlar ƙazanta | ≤2.00% | Ya bi |
| Tsarkake / Hanyar Bincike | ≥98.0% (HPLC) | 99.6% |
| Infrared Spectrum | Yayi daidai da Tsarin | Ya bi |
| 1 H NMR Spectrum | Yayi daidai da Tsarin | Ya bi |
| Kammalawa | An gwada samfurin kuma ya bi ƙayyadaddun da aka bayar | |
Kunshin:Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye akwati sosai kuma a adana a wuri mai sanyi, bushe (2 ~ 8 ℃) da ma'ajin da ke da isasshen iska daga abubuwan da ba su dace ba.Kare daga haske da danshi.
Jirgin ruwa:Isar da shi zuwa duniya ta iska, ta FedEx / DHL Express.Bayar da isarwa cikin sauri kuma abin dogaro.
Wannan samfurin shine 4-Amino-5-Chloro-2,3-Dihydrobenzofuran-7-Carboxylic Acid, abun ciki na C12H12ClNO4 ba zai zama ƙasa da 98.0% ba, ƙididdige shi akan tushen anhydrous.
[Properties] Wannan samfurin ba shi da fari-fari zuwa kauri mai haske-ja.
[Duba]
Ɗauki adadin da ya dace na wannan samfurin (kimanin 0.5g) na ruwa, ƙara ƙarfi (methanol: N, N-dimethylformamide = 50:50), da kuma narkar da shi bisa ga hanyar ƙayyade ruwa (Shafi Ⅷ M, hanyar farko A).Yi amfani da faɗuwar gwajin Fisher don tantancewa har sai maganin ya canza daga rawaya mai haske zuwa ja-launin ruwan kasa mai nunin ƙarshen ƙarshen, da gudanar da wani gwajin mara komai.Yi lissafin bisa ga dabara mai zuwa: abun cikin ruwa kada ya wuce 1.00%.
Abun ciki (%) = (AB) F/W×100%
Inda, A shine adadin ruwan Fisher da samfurin gwajin ya cinye (ml);
B shine ƙarar ruwan gwajin Fisher da babu sarari, ml;
F shine nauyin maganin gwajin Fisher daidai da ruwa a kowace 1ml, mg;
W shine nauyin samfurin gwajin, mg
Abu mai alaƙa
Dangane da hanyar da ke ƙarƙashin "abun auna abun ciki", idan akwai kololuwa na ƙazanta a cikin chromatogram na maganin gwajin, yanki mafi girman ƙazanta ɗaya ba zai fi sau 10 (1.0%) na babban yanki mafi girma na sarrafawa ba. bayani, kuma jimlar yanki mafi girma na duk ƙazanta bazai zama fiye da sau 20 (2.0%) na babban yanki mafi girma na maganin sarrafawa ba.
[Ƙaddarar abun ciki] Dangane da babban aikin chromatography na ruwa (Shafi VI D).
Octadecylsilane bonded silica gel an yi amfani dashi azaman filler don yanayin chromatographic da gwajin dacewa da tsarin.Phosphate buffer bayani (1.36g potassium dihydrogen phosphate, narkar da ultrasonic a cikin 1L ruwa, phosphoric acid gyara zuwa PH 3.0) da aka yi amfani da mobile lokaci A. Acetonitrile ne mobile lokaci B, da gradient elution da aka yi bisa ga tebur mai zuwa:
Lokaci (min) Matakin Wayar hannu A lokacin hannu B
080 20
1580 20
3050 50
45 50 50
Tsayin da aka gano shine 254 nm.Yawan kwarara ya kasance 1.0 ml/min.Yawan faranti na ka'idar ba kasa da 2000 ba bisa ga kololuwar 4-Amino-5-Chloro-2,3-Dihydrobenzofuran-7-Carboxylic Acid.
Kololuwar acid furanoformic bai gaza 2000 ba.
Hanyar tantancewa:
Ɗauki 10mg na samfurin gwajin, auna shi daidai, sanya shi a cikin kwalban 10ml, narke shi ultrasonic tare da lokaci na A-mobile lokaci B (70:30) kamar yadda sauran ƙarfi, tsarma shi zuwa sikelin, girgiza da kyau, kuma shirya bayani tare da maida hankali na 1mg/ml.20 l na daidaito an allura a cikin chromatograph na ruwa, kuma an rubuta chromatogram.Babban tsaftar kololuwa bai gaza 98.0% ba bisa ga hanyar daidaita yankin kololuwa
Tushen: Dionex Acclaim C18, 4.6*250mm, 5um
Yanayin zafin jiki: 40 ℃
Yawan gudu: 1.0ml/min
Tsawon Gano: 254nm
Girman samfurin: 10 μL
Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.
Manyan Kasuwanni?Sayarwa zuwa kasuwannin cikin gida, Arewacin Amurka, Turai, Indiya, Koriya, Jafananci, Australia, da sauransu.
Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.
inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.
Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.
MOQ?Babu MOQ.Karamin tsari abin karɓa ne.
Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.
Sufuri?By Express (FedEx, DHL), ta Air, ta Teku.
Takardu?Bayan sabis na tallace-tallace: COA, MOA, ROS, MSDS, da dai sauransu za a iya ba da su.
Tsarin al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.
Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.
4-Amino-5-Chloro-2,3-Dihydrobenzofuran-7-Carboxylic Acid (CAS: 123654-26-2), za a iya amfani da a matsayin tsaka-tsaki ga kira na Prucalopride Succinate (CAS: 179474-85-2), agonist mai karɓa na 5-HT4 da aka zaɓa wanda aka yi amfani da shi mai tasiri don maƙarƙashiya na yau da kullum.Prucalopride Succinate, dihydrobenzofurancarboxamide-ajin farko, shine mai zaɓaɓɓen mai karɓar mai karɓa na serotonin (5-HT4).Magungunan, wanda aka sayar a ƙarƙashin sunan alamar Resolor®, yana da ayyukan enterokinetic kuma kamfanin samar da magunguna na Belgian Movetis ya haɓaka.Prucalopride yana canza tsarin motsi na colonic ta hanyar serotonin 5-HT4 ƙwaƙƙwarar mai karɓa, yana haifar da ƙarfin motsa jiki na tsakiya don lalata.
