CAS 177036-94-1 Tsafta > 99.0% (HPLC) API Babban Tsabta
Bayar da Kasuwanci (CAS: 177036-94-1) Matsakaici masu alaƙa:
Saukewa: 177036-94-1
Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate CAS: 178306-47-3
2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid CAS: 178306-51-9
(S)-2-Hydroxy-3-Methoxy-3,3-Diphenylpropionic Acid CAS: 178306-52-0
L-Proline Methyl Ester Hydrochlorid CAS: 2133-40-6
4,6-Dimethyl-2- (Methylsulfonyl) pyrimidine CAS: 35144-22-0
Sunan Sinadari | (S)-2-[(4,6-Dimethylpyrimidin-2-yl) oxy] -3-Methoxy-3,3-Diphenylpropionic Acid |
Makamantu | (+-) (2S) -2-((4,6-Dimethylpyrimidin-2-yl) oxy) -3-Methoxy-3,3-Diphenylpropanoic Acid |
Lambar CAS | 177036-94-1 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C22H22N2O4 |
Nauyin Kwayoyin Halitta | 378.43 |
Takamaiman Juyawa [α]D20 | +170.0° zuwa +176.0° (C=0.5, MeOH) |
Matsayin narkewa | 172.0 ~ 178.0 ℃ |
Solubility | Soluble sosai a cikin methanol;Mai narkewa a cikin Ethanol, acetone;Mara narkewa a cikin Ruwa |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari ko Kashe-Farin Foda |
Ganewa | HPLC;NMR;LC-MS |
Abubuwa masu alaƙa | |
Rashin Tsabtace Mutum | ≤0.50% |
Jimlar ƙazanta | <1.00% |
Asara akan bushewa | ≤0.50% |
Ragowa akan Ignition | ≤0.20% |
Karfe masu nauyi | ≤20ppm |
Tsarkake / Hanyar Bincike | > 99.0% (HPLC) |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaicin Magunguna |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
(CAS: 177036-94-1) APIne mai zaɓaɓɓen endothelin-A (ETA) antagonist mai karɓa wanda aka gabatar don maganin baka na marasa lafiya tare da hauhawar jini na huhu (PAH), don inganta ƙarfin motsa jiki da jinkirta jinkirin asibiti.PAH wata cuta ce da ba a sani ba na ƙananan jijiyoyi na huhu wanda ke da alaƙa da haɓakar ƙwayoyin cuta da gyare-gyare, wanda ya haifar da ci gaba a cikin juriya na huhu da kuma matsa lamba na huhu, kuma a ƙarshe, rashin cin nasara na ventricular dama da kuma mutuwa da wuri.Alamomin farko na PAH sun haɗa da farawa a hankali na ƙarancin numfashi, gajiya, bugun zuciya, edema, da suma.Endothelin-1 (ET-1), wani m vasoconstrictor da santsi tsoka mitogen, shi ne mabuɗin mai ba da gudummawa ga haɓakar cutar, kuma ana yin sulhunta tasirinta ta hanyar kunna ETA da masu karɓar ETB.A watan Yuni na 2007, FDA ta ba da izinin (CAS: 177036-94-1) API don maganin PAH sau ɗaya kowace rana.