6,7-Bis (2-Methoxyethoxy) -4 (3H) -Quinazolinone CAS 179688-29-0 Erlotinib Hydrochloride Tsabtace Tsabtace>99.0% (HPLC)
Jagoran masana'anta da mai siyar da Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis (2-Methoxyethoxy) -3H-Quinazolin-4-daya CAS 179688-29-0
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Sunan Sinadari | 6,7-Bis (2-Methoxyethoxy) -3H-Quinazolin-4-daya |
Makamantu | 6,7-Bis (2-Methoxyethoxy) -4 (3H) - Quinazolinone;6,7-Bis (2-Methoxyethoxy) -3,4-Dihydroquinazolin-4-daya;6,7-Bis (2-Methoxyethoxy) -4-Hydroxyquinazoline;6,7-Bis (2-Methoxyethoxy) -4-Quinazolinol;Saukewa: CP-380736 |
Rashin tsarki | Erlotinib rashin tsabta A;Erlotinib Lactam rashin tsabta |
Lambar CAS | 179688-29-0 |
Lambar CAT | Saukewa: RF2685 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C14H18N2O5 |
Nauyin Kwayoyin Halitta | 294.31 |
Matsayin narkewa | 190.0 zuwa 194.0 ℃ |
Yawan yawa | 1.26± 0.1 g/cm3 |
M | Hankalin iska |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari ko Kashe-Farin Foda |
Tsarkake / Hanyar Bincike | > 99.0% (HPLC) |
Matsayin narkewa | 190.0 zuwa 194.0 ℃ |
Asara akan bushewa | <0.50% |
Ragowa akan Ignition | <0.20% |
Abubuwan da ke da alaƙa ta HPLC | |
Rashin Tsabtace Mutum | <0.50% |
Jimlar ƙazanta | <1.00% |
Karfe masu nauyi | <10ppm |
Infrared Spectrum | Yayi daidai da Tsarin |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaicin Erlotinib Hydrochloride (CAS: 183319-69-9) |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
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6,7-Bis (2-Methoxyethoxy) -3H-Quinazolin-4-one (CAS: 179688-29-0) matsakaici ne na Erlotinib Hydrochloride (CAS: 183319-69-9).Erlotinib Hydrochlorate ƙaramin ƙwayar tyrosine kinase inhibitor ne wanda ke yin jujjuyawar akan masu karɓar haɓakar girma na epidermal, hydrochloride na erlotinib, maganin da aka yi niyya na ƙwayoyin cuta.Hukumar Abinci da Magunguna ta Amurka (FDA) ta amince da erlotinib (Tarceva) tare da gemcitabine a matsayin jiyya ta farko don ci gaban gida da ciwon daji na pancreatic.Ana amfani da shi galibi azaman magani na layi na biyu ko na uku don ci gaba a cikin gida ko ciwon daji mara ƙarami (NSCLC) kuma azaman maganin kansar pancreatic.Ana amfani dashi azaman mai hana tyrosine don maganin NSCLC.Ƙananan ƙwayoyin ƙwayoyin cuta Erlotinib Hydrochlorate shine mai hana mai karɓa na tyrosine kinase wanda ke hana yaduwar ƙwayoyin tumor ta hanyar hana phosphorylation, ɗaure zuwa yankin catalytic na intracellular na tyrosine kinase a cikin gasa tare da ATP, don haka yana toshe siginar siginar ƙasa da kuma hana ayyukan ƙwayar ƙwayar ƙwayar cuta. HER-1/EGFR.