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Ibrutinib Intermediate CAS 330792-70-6 Tsarkake> 98.0% (HPLC) Hoton da aka Fitar
  • Ibrutinib Intermediate CAS 330792-70-6 Tsarkake>98.0% (HPLC)

Ibrutinib Intermediate CAS 330792-70-6 Tsarkake>98.0% (HPLC)

Takaitaccen Bayani:

5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile

Saukewa: 330792-70-6

Tsafta:> 98.0% (HPLC)

Bayyanar: Kashe-Fara zuwa Foda Rawaya mai Haske

Matsakaicin Ibrutinib (CAS: 936563-96-1) 

Tuntuɓi: Dr. Alvin Huang

Wayar hannu/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Cikakken Bayani

Samfura masu dangantaka

Tags samfurin

Matsakaicin Ibrutinib:

Ibrutinib Farashin 936563-96-1
3-Hydroxypiperidine Farashin 6859-99-0
1-Boc-3-Hydroxypiperidine Saukewa: CAS85275-45-2
(S)-1-Boc-3-Hydroxypiperidine Farashin 143900-44-1
4-Phenoxybenzoic Acid Saukewa: CAS2215-77-2
4-Phenoxyphenylboronic Acid Saukewa: CAS51067-38-0
4-Aminopyrazolo[3,4-d] pyrimidine Saukewa: CAS2380-63-4
4-Amino-3-Iodo-1H-Pyrazolo[3,4-d] pyrimidine Saukewa: CAS151266-23-8
Ibrutinib Deacryloylpiperidine Saukewa: CAS330786-24-8
5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile Saukewa: CAS330792-70-6

Abubuwan Sinadarai:

Sunan Sinadari 5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Makamantu Ibrutinib Matsakaici N-3;3-Amino-5- (4-Phenoxyphenyl) pyrazole-4-Carbonitrile;3-Amino-4-Cyano-5- (4-Phenoxyphenyl) pyrazole;5-Amino-3-(4-Phenoxyphenyl)-1H-Pyrazole-4-Carbonitrile
Lambar CAS 330792-70-6
Matsayin Hannun jari A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton
Tsarin kwayoyin halitta Saukewa: C16H12N4O
Nauyin Kwayoyin Halitta 276.29
Yawan yawa 1.37± 0.10 g/cm3
COA & MSDS Akwai
Asalin Shanghai, China
Alamar Ruifu Chemical

Ƙayyadaddun bayanai:

Abu Ƙayyadaddun bayanai
Bayyanar Kashe-Fara Zuwa Hasken Foda na Yellow
Tsarkake / Hanyar Bincike 98.0% (HPLC)
Asara akan bushewa <1.00%
Ragowa akan Ignition <0.50%
Jimlar ƙazanta <2.00%
Karfe masu nauyi (kamar Pb) <20ppm
1 H NMR Spectrum Daidai da Tsarin
Matsayin Gwaji Matsayin Kasuwanci
Amfani Matsakaicin Ibrutinib (CAS: 936563-96-1)

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi.

Amfani:

1

FAQ:

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330792-70-6 - Aikace-aikace:

5-Amino-3- (4-Phenoxyphenyl) -1H-Pyrazole-4-Carbonitrile (CAS: 330792-70-6) shine tsaka-tsakin Ibrutinib (CAS: 936563-96-1).Ibrutinib yana nuna tasirin hanawa mai ƙarfi da mara ƙarfi da zaɓi don ayyukan enzymatic Btk.A cikin layin BCR da aka kunna DOHH2, Ibrutinib ya hana autophosphorylation na Btk, phosphorylation na Btk's physiological substrate PLCγ, da phosphorylation na kara downstream kinase, ERK tare da IC50 na 11 nM, 29 nM da 13 nM bi da bi.Ibrutinib yana nuna mahimmancin kashi-dogara da shigar da cytotoxicity a cikin ƙwayoyin cutar sankarar jini na lymphocytic (CLL).Bugu da ƙari, Ibrutinib yana haifar da mutuwar tantanin halitta dangane da kunnawa ta hanyar caspase kuma yana adawa da ikon ƙwayoyin CLL don yaduwa bayan siginar TLR.

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