Lapatinib Ditosylate Monohydrate CAS 388082-78-8 Tsafta>99.0% (HPLC)
Sunan Sinadari | Lapatinib Ditosylate Monohydrate |
Makamantu | N-[3-chloro-4-[(3-fluorophenyl) methoxy] phenyl]-6-[5-[(2-methylsulfonylethylamino) methyl]furan-2-yl] quinazolin-4-amine |
Lambar CAS | 388082-78-8 |
Matsayin Hannun jari | A Stock |
Tsarin kwayoyin halitta | C29H26ClFN4O4S·2(C7H8O3S)·H2O |
Nauyin Kwayoyin Halitta | 943.48 |
COA & MSDS | Akwai |
Asalin | Shanghai, China |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Kodadde Rawaya zuwa Yellow Crystalline Foda |
Tsarkake / Hanyar Bincike | ≥99.0% (HPLC) |
Matsayin narkewa | 240.0 ~ 242.0 ℃ |
Danshi (KF) | 1.9 ~ 2.4% |
Tsaftace Guda Daya | ≤0.50% |
Jimlar ƙazanta | ≤1.00% |
Karfe masu nauyi (kamar Pb) | ≤20ppm |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | API;Domin maganin masu fama da ciwon nono |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
Lapatinib Ditosylate Monohydrate (CAS: 388082-78-8) shine gishiri ditosylateSaukewa: CAS231277-92-2, wani roba, quinazoline mai aiki da baki tare da yuwuwar aikin antineoplastic.Yana sake toshe phosphorylation na epidermal girma factor receptor (EGFR), ErbB2, da Erk-1 da-2 da AKT kinases;Hakanan yana hana matakan furotin na cyclin D a cikin layin ƙwayoyin ƙwayar cuta na ɗan adam da xenografts.EGFR da ErbB2 sun kasance cikin haɓakar nau'ikan ƙari daban-daban.An ƙaddamar da shi don kula da ci-gaba ko metastatic HER2 (ErbB2) tabbataccen ciwon nono a cikin matan da suka karɓi maganin farko.GlaxoSmithKline ne ya gano kuma ya haɓaka maganin.