DAPT (GSI-IX) CAS 208255-80-5 γ-Secretase Inhibitor Assay> 98.0% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta na DAPT (GSI-IX) (CAS: 208255-80-5) tare da babban inganci, γ-Secretase Inhibitor.Ruifu Chemical yana ba da jerin amino acid da abubuwan da aka samo asali.Za mu iya samar da isar da sako na duniya, ƙanana da girma da yawa akwai.Sayi DAPT,Please contact: alvin@ruifuchem.com
| Sunan Sinadari | DAPT |
| Makamantu | GSI-IX;γ-Secretase Inhibitor IX;Mai hana gamma-Secretase;LY-374973;(3,5-Difluorophenylacetyl) -Ala-Phg-OtBu;(3,5-Difluorophenylacetyl) -L-Alanyl-L-2-Phenylglycine tert-Butyl Ester;N-[N- (3,5-Difluorophenacetyl)-L-Alanyl] -S-Phenylglycine t-Butyl Ester;(2S)-N-[2- (3,5-Difluorophenyl) acetyl] -L-Alanyl-2-Phenyl-glycine 1,1-Dimethylethyl Ester |
| Matsayin Hannun jari | A Stock |
| Lambar CAS | 208255-80-5 |
| Tsarin kwayoyin halitta | Saukewa: C23H26F2N2O4 |
| Nauyin Kwayoyin Halitta | 432.47 |
| Yawan yawa | 1.213 g/cm 3 |
| Matsayin narkewa | 142.0 ~ 146.0 ℃ |
| M | Zafi Sensitive |
| Solubility | Mai narkewa a cikin DMSO |
| Adana Yanayin. | Adana a 2-8 ℃ |
| COA & MSDS | Akwai |
| Alamar | Ruifu Chemical |
| Bayanan Tsaro | 24/25 - Guji hulɗa da fata da idanu. | ||
| WGK Jamus | 3 | HS Code | 2922491990 |
| Abubuwa | Ka'idojin dubawa | Sakamako |
| Bayyanar | Fari ko Kashe-White Crystalline Foda | Ya dace |
| Asara akan bushewa | <0.40% | 0.21% |
| Ragowa akan Ignition | <0.40% | 0.20% |
| Karfe masu nauyi (kamar Pb) | ≤20ppm | <20ppm |
| Hanyar Assay / Analysis | 98.0% (HPLC) | 98.62% |
| Carbon ta Elemental Analysis | 62.1 ~ 64.1% | Ya dace |
| Nitrogen ta Elemental Analysis | 6.20 ~ 6.70% | Ya dace |
| Infrared Spectrum | Yayi daidai da Tsarin | Ya dace |
| Farashin NMR Spectrum | Yayi daidai da Tsarin | Ya dace |
| Kammalawa | Wannan Samfura ta Yarjejeniyar Bincike tare da Matsayin Kasuwanci | |
| Rayuwar Rayuwa | Watanni 24 Daga Ranar Ƙirƙira Idan An Ajiye shi Da kyau | |
Kunshin: Fluorinated Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a sanyi, bushe (ajiya a 2-8 ℃) da ɗakin ajiyar iska daga abubuwan da ba su dace ba.Kare daga haske da danshi.
Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.
Manyan Kasuwanni?Sayarwa zuwa kasuwannin cikin gida, Arewacin Amurka, Turai, Indiya, Koriya, Jafananci, Australia, da sauransu.
Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.
inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.
Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.
MOQ?Babu MOQ.Karamin tsari abin karɓa ne.
Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.
Sufuri?By Express (FedEx, DHL), ta Air, ta Teku.
Takardu?Bayan sabis na tallace-tallace: COA, MOA, ROS, MSDS, da dai sauransu za a iya ba da su.
Haɗin Kan Al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.
Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.
DAPT (GSI-IX) (CAS: 208255-80-5), mai ƙarfi da takamaiman mai hana γ-asiri.DAPT shine mai hana γ-secretase (IC50 a cikin ƙananan ƙananan ƙananan mutane = 115 nM don jimlar Aβ ko 200 nM don Aβ42 musamman).An nuna ikon sarrafa baki na DAPT don rage matakan Aβ a cikin cirewar kwakwalwa, ruwan cerebrospinal da plasma daga mice da berayen.DAPT yana toshe siginar Notch wanda ke haɓaka bambance-bambancen jijiyoyi na sel precursor.Yana haɓaka ƙwayoyin iPS ba tare da oncogenes KLF4 da CMYC5 ba.Tantanin halitta.Ana amfani da DAPT a cikin nazarin samuwar β-amyloid.An nuna DAPT don hana siginar Notch a cikin nazarin cututtuka na autoimmune da lymphoproliferative, irin su ALPS da lupus erythematosus, da kuma ci gaban kwayar cutar kansa, angiogenesis, da kuma bambanta nau'in sel mai ƙarfi da ɗan adam ya haifar.Yana hana siginar Notch a cikin vitro.Yana hana duka samar da Aβ da Aβ42 a cikin al'adun farko na ɗan adam (ƙimar IC50 sune 115 da 200 nM, bi da bi) ba tare da tasiri akan matakan APPα da APPβ ba.Shamakin jini-kwakwalwa mai yuwuwa.3D Growth matrix bangaren da bangaren cerebral organoid kafofin watsa labarai bambanta.
