Darunavir CAS 206361-99-1 Tsabtace Tsabtace-HIV
Samar da masana'antaAbubuwan da suka danganci Darunavir:
Darunavir CAS 206361-99-1
Darunavir Ethanolate CAS 635728-49-3
(2S,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98737-29-2
(2R,3S)-1,2-Epoxy-3-(Boc-Amino)-4-Phenylbutane CAS 98760-08-8
(3S)-3-(tert-Butoxycarbonyl)amino-1-Chloro-4-Phenyl-2-Butanone CAS 102123-74-0
Sunan Sinadari | Darunavir |
Makamantu | TMC114;UIC-94017 |
Lambar CAS | 206361-99-1 |
Lambar CAT | RF-API68 |
Matsayin Hannun jari | A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram |
Tsarin kwayoyin halitta | Saukewa: C27H37N3O7S |
Nauyin Kwayoyin Halitta | 547.66 |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari ko Kashe-White Crystalline Foda |
Ganewa | MS/HNMR HPLC |
Solubility | Mai narkewa a cikin DMSO, Dan Soluble a Ruwa |
Matsayin narkewa | 74.0 ~ 76.0 ℃ |
Ganewa | 1H NMR |
Tsarkake / Hanyar Bincike | ≥99.0% (HPLC) |
Abubuwa masu alaƙa | |
Max Single Najasa | ≤0.30% |
Jimlar ƙazanta | ≤1.0% |
Ragowar Magani | Ethanol ≤0.30% |
Asara akan bushewa | ≤0.50% |
Ragowa akan Ignition | ≤0.10% |
Karfe masu nauyi | ≤20ppm |
Arsenic | ≤1.5pm |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Darunavir (CAS 206361-99-1) Mai hana HIV-1 Protease Inhibitor Anti-HIV |
Kunshin: Bottle, Aluminum tsare jakar, Kwali Drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
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Darunavir (sunan suna Prezista, wanda aka fi sani da TMC114) magani ne mai hana protease da ake amfani dashi don magance kamuwa da cutar HIV.Darunavir wani zaɓi ne na OARAC da aka ba da shawarar magani don jiyya-rashin hankali da ƙwarewar jiyya manya da matasa.Darunavir wani sabon nau'i ne na marasa peptide anti retroviral protease inhibitors a maganin AIDS.Kamfanin Johnson Pharmaceutical Iceland reshen Tibotec ne ya fara haɓaka shi.Yana daga cikin mafi girma na bioavailability a cikin masu hana protease 6 (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir da ABT378/r).Yana aiki ta hanyar toshe samuwar sabbin ƙwayoyin ƙwayoyin cuta waɗanda suka balaga daga saman ƙwayoyin ƙwayoyin cuta da ke hana ƙwayoyin cuta.Lokacin da aka yi amfani da samfurin na dogon lokaci, yawanci yana iya rage ƙwayar cutar HIV a cikin jini, ƙara yawan adadin CD4, rage yiwuwar kamuwa da cutar HIV, inganta yanayin rayuwa da kuma tsawaita rayuwa.Ya dace da manya waɗanda ke ɗauke da kwayar cutar HIV amma ba su da tasiri a kan amfani da magungunan rigakafin da ke akwai.Dole ne a haɗa miyagun ƙwayoyi tare da yin amfani da ƙananan allurai na ritonavir ko wasu magungunan antiretroviral, don inganta tasiri.Ayyukan antiviral a cikin vitro za a iya ƙididdige su ta hanyar yin tsayayya da ƙananan ƙwayoyin lymphocytes masu kamuwa da cuta da lymphocytes a cikin jini na gefe.