Darunavir Ethanolate CAS 635728-49-3 Tsabtace ≥99.0% API Factory Anti-HIV HIV Protease Inhibitor

Takaitaccen Bayani:

Chemical Name: Darunavir Ethanolate

Saukewa: 635728-49-3

Bayyanar: Fari ko Kashe-White Crystalline Foda

Tsafta: ≥99.0%

Marasa peptide HIV Protease Inhibitor Anti-HIV

API High Quality, Kasuwancin Kasuwanci

Inquiry: alvin@ruifuchem.com


Cikakken Bayani

Samfura masu dangantaka

Tags samfurin

Bayani:

Abubuwan Sinadarai:

Sunan Sinadari Darunavir Ethanolate
Makamantu DRV;Prezista;TMC114 Ethanolate;UNII-33O78XF0BW;N-[(1S,2R) -3-[(4-Aminophenyl) sulfonyl] (2-methylpropyl) amino] -2-hydroxy-1- (phenylmethyl) propyl] carbamic acid (3R,3aS,6aR) -hexahydrofur [2,3-b]furan-3-yl ester compd.tare da ethanol
Lambar CAS 635728-49-3
Lambar CAT RF-API69
Matsayin Hannun jari A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram
Tsarin kwayoyin halitta Saukewa: C29H43N3O8S
Nauyin Kwayoyin Halitta 593.73
Alamar Ruifu Chemical

Ƙayyadaddun bayanai:

Abu Ƙayyadaddun bayanai
Bayyanar Fari ko Kashe-White Crystalline Foda
Gano IR Yayi daidai da Standard Spectrum
Takamaiman Juyawa -0.5°~ +0.5°
Abubuwa masu alaƙa (da HPLC)
Max Single Najasa ≤0.20%
Jimlar ƙazanta ≤0.50%
Ruwa (KF) ≤1.0%
Ragowa akan Ignition ≤0.10%
Karfe masu nauyi ≤10ppm
Abun ciki na Ethanol ≤7.5% (GC)
Ragowar Magani Methanol ≤0.30%
Tsafta ≥99.0% (HPLC)
Matsayin Gwaji Matsayin Kasuwanci
Amfani Darunavir Ethanolate HIV-1 Protease Inhibitor Anti-HIV Antiviral

Kunshin & Ajiya:

Kunshin: Bottle, Aluminum tsare jakar, Kwali Drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.

Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.

Amfani:

1

FAQ:

Aikace-aikace:

Darunavir Ethanolate (Prezista) mai hana cutar HIV ne.Abubuwan da aka samu na Darunavir, mai hana cutar HIV-1-protease na ƙarni na biyu;tsarin kama da amprenavir.Antiviral.samfuri ne mai alaƙa da COVID19.Abin takaici, DRV yana da ƙarancin narkewa a cikin ruwa da ƙarancin rayuwa, don haka yana buƙatar gudanarwa a cikin ƙananan allurai don nuna ingancin warkewa.Darunavir babban mai hanawa ne mai faɗin bakan mai aiki da keɓewar asibiti na HIV-1 tare da ƙarancin cytotoxicity.Darunavir yana samar da haɗin gwiwar hydrogen tare da adana babban sarkar atom na Asp29 da Asp30 na protease.Ana ba da shawarar waɗannan hulɗar don zama masu mahimmanci ga ƙarfin wannan fili game da keɓancewar HIV waɗanda ke da juriya ga masu hana protease da yawa.A cikin binciken in vitro a cikin ƙwayoyin MT-2, ƙarfin darunavir ya fi na saquinavir, amprenavir, nelfinavir, indinavir, lopinavir da ritonavir.Darunavir yana haɓaka da farko ta hanyar enzymes cytochrome P450 (CYP), da farko CYP3A.Kashi na 'ƙarfafa' ritonavir yana aiki da mai hana CYP3A, ta haka yana haɓaka bioavailability na darunavir.An ƙera Darunavir don samar da ƙaƙƙarfan hulɗa tare da enzyme na protease daga nau'ikan HIV da yawa, gami da nau'ikan majinyata da suka ƙware tare da mutati juriya da yawa.

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