Decitabine CAS 2353-33-5 Tsarkake> 99.5% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta kuma mai ba da kaya na Decitabine (CAS: 2353-33-5) tare da inganci mai inganci.Za mu iya samar da COA, isarwa a duniya, ƙanana da yawa da ake samu.Idan kuna sha'awar wannan samfurin, da fatan za a aiko da cikakken bayani ya haɗa da lambar CAS, sunan samfur, yawa gare mu.Please contact: alvin@ruifuchem.com
| Sunan Sinadari | Decitabine |
| Makamantu | 5-Aza-2'-Deoxycytidine;5-Aza-1- (2-Deoxy-β-D-Ribofuranosyl) cytosine;5-Aza-CdR;5-Aza-dC;5-Deoxy-2'-Azacytidine;ZdCyd;DAC;β-Decitabine |
| Lambar CAS | 2353-33-5 |
| Lambar CAT | Saukewa: RF2728 |
| Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
| Tsarin kwayoyin halitta | Saukewa: C8H12N4O4 |
| Nauyin Kwayoyin Halitta | 228.21 |
| Matsayin narkewa | 191 ℃ (Dec.) |
| M | Hankalin iska, Mai jin zafi |
| Solubility | Narkar da a DMSO;Dan Soluble A Ruwa |
| Alamar | Ruifu Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Fari ko Kashe-White Crystalline Foda |
| Identification A | IR: Samfuran IR Spectrum yayi Daidai da na Ma'auni |
| Identity B | HPLC: RT na Babban Kololuwar Maganin Gwajin Yayi Daidai da na Ma'aunin Magani |
| Gano C | PXRD: Madalla |
| Tsarkake / Hanyar Bincike | > 99.5% (HPLC) |
| Alfa | +56.0° ~ 63.0° |
| Asara akan bushewa | <0.50% |
| Ragowa akan Ignition | <0.10% |
| Karfe masu nauyi | <20ppm |
| Abubuwa masu alaƙa | |
| α-Decitabine | <0.20% |
| Rashin Tsabtace Guda Daya da Ba'a Sani ba | <0.20% |
| Jimlar ƙazanta | <0.50% |
| Ragowar Magani | |
| DMSO | <0.50% |
| Methanol | <0.30% |
| Methyl Formate | <0.05% |
| Acetonitrile | <0.041% |
| Solubility | Ba tare da Launi Mai launi ba 50 mg/ml, HOAc da H2O (1:1) Wuce |
| Matsayin Gwaji | Matsayin Kasuwanci |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / kwali Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
Yadda ake siya?Please contact: sales@ruifuchem.com or alvin@ruifuchem.com
Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.
Manyan Kasuwanni?Sayarwa zuwa kasuwannin gida, Arewacin Amurka, Turai, Indiya, Rasha, Koriya, Jafananci, Australia, da sauransu.
Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.
inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.
Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.
MOQ?Babu MOQ.Karamin tsari abin karɓa ne.
Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.
Sufuri?By Express (FedEx, DHL), ta Air, ta Teku.
Takardu?Bayan sabis na tallace-tallace: COA, MOA, ROS, MSDS, da dai sauransu za a iya ba da su.
Tsarin al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.
Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.
Decitabine (CAS: 2353-33-5) (sunan kasuwanci Dacogen), ko 5-Aza-2'-Deoxycytidine.A kimiyyance, shi ne cytidine analog.Decitabine wakili ne na hypomethylating.An ƙaddamar da Decitabine don maganin cututtuka na myelodysplastic (MDS).MDS wani tsari ne na cututtukan jini da ke shafar kasusuwan kasusuwa wanda ke haifar da samuwar rashin tasiri da haɓakar ƙwayoyin jini.Bugu da ƙari kuma, marasa lafiya tare da MDS suna da babban haɗari na ci gaba zuwa m myeloid leukemia (AML).Jiyya na al'ada sun haɗa da ƙarin jini, abubuwan haɓakar hematopoietic, da rigakafin rigakafi, amma waɗannan matakan suna haɓaka ingancin rayuwa kawai tare da abubuwan da za a iya tambaya akan gyare-gyaren cuta.Yayin da dashen sel-tsalle abu ne mai tsauri, mai yuwuwar hanyar warkewa, tsufa ko sauran matsalolin lafiya masu rikitarwa na yawancin marasa lafiya sun hana su yin la'akari da wannan zaɓi.Ci gaba na baya-bayan nan a cikin ilimin asali na MDS, duk da haka, ya haifar da haɓaka sabon nau'in mahadi da aka sani da '' demethylating agents ''.Decitabine ya biyo bayan gabatarwar nasara na farko na DNA methyltransferase inhibitor Azacitidine.Yana hypomethylates DNA ta hanyar hana DNA methyltransferase.Yana aiki daidai da Azacitidine, kodayake decitabine kawai za'a iya shigar dashi cikin sassan DNA yayin da za'a iya shigar da azacitidine cikin sassan DNA da RNA.Reagents na bincike: Ana amfani da Decitabine sosai a cikin ilimin halittar kwayoyin halitta, ilimin harhada magunguna, da sauran binciken kimiyya.Decitabine a matsayin takamaiman DNA methyltransferase inhibitor, tsarin DNA methylation mai jujjuyawar, haifar da ƙwayoyin tumo zuwa sel na al'ada don bambanta ko haifar da apoptosis cell tumor.Yi la'akari da cewa babban taro na Decitabine zai kunna tasirin cytotoxic: zai iya hana haɗin DNA wanda ya haifar da mutuwar kwayar halitta.
