Diethylphosphonoacetic Acid CAS 3095-95-2 Tsarkake>99.5% (HPLC) Afatinib Dimaleate Tsakanin Factory
Ruifu Chemical Supply Intermediates of Afatinib
Afatirib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino) acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H) -daya CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl) oxy) quinazoline-4,6-DiamineSaukewa: CAS314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy) quinazolin-4-AmineSaukewa: CAS314771-88-5
Sunan Sinadari | Diethylphosphonoacetic acid |
Makamantu | 2- (Diethoxyphosphosphoryl) acetic acid;(Diethoxyphosphinyl) acetic acid;Diethyl Carboxymethylphosphonate;Saukewa: NSC272281 |
Lambar CAS | 3095-95-2 |
Lambar CAT | Saukewa: RF-PI2024 |
Matsayin Hannun jari | A cikin Hannun jari, Ƙarfin Ƙirƙirar 30MT/ Watan |
Tsarin kwayoyin halitta | (C2H5O) 2P (O) CH2CO2H |
Nauyin Kwayoyin Halitta | 196.14 |
Wurin Tafasa | 150 ℃/0.05 mmHg (lit.) |
Yawan yawa | 1.220 g/ml a 25 ℃ (lit.) |
Fihirisar Refractive | n20/D 1.445 (lit.) |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Ruwa mara launi |
Identification (HPLC) | Lokacin riƙewa na babban tsayin da aka samu daga samfurin yana cikin 5% na samfurin tunani. |
Tsarkake / Hanyar Bincike | > 99.5% (HPLC) |
Infrared Spectrum | Yayi daidai da Tsarin |
Abubuwan da aka bayar na Proton NMR Spectrum | Yayi daidai da Tsarin |
Danshi (KF) | <0.50% |
Jimlar ƙazanta | <0.50% |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaicin Afatinib Dimaleate (CAS: 850140-73-7) |
Kunshin: Fluorinated kwalban, 25kg / Drum, ko bisa ga abokin ciniki ta bukata
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi
Diethylphosphonoacetic Acid (CAS: 3095-95-2), Ayyukan aiki azaman nucleophile don haɓaka haɓakar haɓakar nucleophilic don haɓakar allene epoxides Reactant don: Nazarin stereoselectivity na halayen Staudinger;Enantioselective samuwar diols ta hanyar epioxidation da halayen hydration;Halayen Horner-Wadsworth-Emmons;Chelation mai nisa sarrafa Ireland-Claisen sake tsarawa;halayen Ugi-Dieckmann don haɓakar abubuwan da aka samo tetramic acid;Ana amfani dashi don yin tsaka-tsakin phosphonoester don halayen HEW na intramolecular.Diethylphosphonoacetic acid shine matsakaici na Afatinib Dimaleate (CAS: 850140-73-7).Hukumar Kula da Abinci da Magunguna ta Amurka (FDA) ta amince da Afatinib Dimaleate a shekarar 2013 don maganin cutar kansar huhun mara kanana (NSCLC).Musamman, an yarda da shi ga marasa lafiya waɗanda ke gabatar da ciwace-ciwacen ƙwayoyin cuta na NSCLC waɗanda ke ɗauke da gogewar haɓakar haɓakar haɓakar epidermal (EGFR) ko maye gurbin exon 21.Afatinib Dimaleate mai hanawa ne na ErbB tyrosine kinases (tyk), wanda ke lalata siginar ErbB ta hanyar daurin EGFR tyk maras canzawa.