Doxorubicin Hydrochloride CAS 25316-40-9 API USP Standard Factory High Purity
Mai ƙera tare da Babban Tsafta da Ƙarfin Ƙarfi
Sunan Sinadari: Doxorubicin Hydrochloride
Saukewa: 25316-40-9
Wakilin Antitumor Antibiotic.Yana hana DNA Topoisomerase II
API High Quality, Kasuwancin Kasuwanci
Sunan Sinadari | Doxorubicin Hydrochloride |
Makamantu | Doxorubicin HCl;Adriamycin HCL;Hydroxydaunorubicin Hydrochloride |
Lambar CAS | 25316-40-9 |
Lambar CAT | RF-API38 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C27H30ClNO11 |
Nauyin Kwayoyin Halitta | 579.98 |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Orange-Red ko Red Crystalline Foda;Babu wata shaida a bayyane na gurɓata al'amuran waje |
Solubility | Mai narkewa a cikin ruwa da methanol;dan kadan mai narkewa a cikin ethanol;kusan ba zai iya narkewa a cikin acetone |
Identification A | Bakan IR yayi daidai da bakan IR na ma'aunin tunani |
Identity B | Lokacin riƙewa na doxorubicin kololuwa a cikin chromatogram na shirye-shiryen Assay ya dace da abin da ke cikin chromatogram na Shirye-shiryen Daidaitawa, kamar yadda aka samu a cikin Assay. |
pH | 4.0 ~ 5.5 |
Abubuwan Ruwa | ≤4.0% |
Abubuwa masu alaƙa | |
Najasa A (Doxorubicinol) | ≤0.50% |
Duk Wani Rashin Najasa Ba a Sani ba | ≤0.20% |
Jimlar Abubuwan da ba a sani ba | ≤0.50% |
Jimlar ƙazanta | ≤1.0% |
Assay | 98.0% ~ 102.0% na C27H30ClNO11 an ƙididdige su akan tushen anhydrous, mara ƙarfi. |
Ragowar Magani | |
Acetone | ≤0.50% |
Ethanol + acetone | ≤2.5% |
Methanol | ≤0.30% |
Dichloromethane | ≤0.06% |
Matsayin Gwaji | Ma'aunin Magana na Pharmacopeia na Amurka (USP). |
Amfani | Sinadarin Magunguna Mai Aiki (API) |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta kuma mai samar da Doxorubicin Hydrochloride (CAS: 25316-40-9) tare da inganci mai inganci.Doxorubicin hydrochloride, maganin rigakafi na cytotoxic anthracycline, wakili ne na maganin ciwon daji na chemotherapy.Doxorubicin hydrochloride shine ɗan adam DNA topoisomerase I da topoisomerase II inhibitor tare da IC50s na 0.8 μM da 2.67 μM, bi da bi.Doxorubicin hydrochloride yana haifar da apoptosis da autophagy.Doxorubicin wakili ne mai ƙarfi na antitumour mai aiki akan nau'ikan cututtuka masu yawa, waɗanda suka haɗa da cutar sankarar bargo, sarcomas, kansar nono, ƙananan ƙwayar huhu da kansar kwai.