EDC · HCl CAS 25952-53-8 Haɗaɗɗen Reagent Tsabta> 99.0% (T) Hoton Factory

EDC · HCl CAS 25952-53-8 Haɗaɗɗen Reagent Tsarkake> 99.0% (T) Factory

Takaitaccen Bayani:

1- (3-Dimethylaminopropyl) -3-Ethylcarbodiimide Hydrochloride

Synonyms: EDC · HCl

Saukewa: 25952-53-8

Tsafta:>99.0% (Argentmetric Titration)

Bayyanar: Farin Crystalline Foda

Haɗin kai Reagent don Peptides Synthesis

Tuntuɓi: Dr. Alvin Huang

Wayar hannu/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Cikakken Bayani

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Bayani:

Shanghai Ruifu Chemical Co., Ltd. shine babban kamfani na 1- (3-Dimethylaminopropyl) -3-Ethylcarbodiimide Hydrochloride (EDC · HCl) (CAS: 25952-53-8) tare da babban inganci.Ruifu Chemical yana ba da jerin abubuwan kariya da reagents masu haɗawa.Ruifu na iya samar da isar da saƙo na duniya, farashi mai gasa, ƙanana da yawa da ake samu.Sayi EDC·HCl,Please contact: alvin@ruifuchem.com

Abubuwan Sinadarai:

Sunan Sinadari	1- (3-Dimethylaminopropyl) -3-Ethylcarbodiimide Hydrochloride
Makamantu	EDC · HCl;EDAC · HCl;EDCI · HCl;EDC Hydrochloride;EDAC Hydrochloride;N- (3-Dimethylaminopropyl) -N'-Ethylcarbodiimide Hydrochloride;1-Ethyl-3- (3-Dimethylaminopropyl) carbondiimide Hydrochloride;N-Ethyl-N'- (3-dimethylaminopropyl) carbodiimide Hydrochloride;Ruwa mai Soluble Carbodiimide
Matsayin Hannun jari	A Stock, Mass Production
Lambar CAS	25952-53-8
Tsarin kwayoyin halitta	C8H17N3 · HCl
Nauyin Kwayoyin Halitta	191.70 g / mol
Matsayin narkewa	110.0 ~ 115.0 ℃
Yawan yawa	0.877 g/ml a 20 ℃ (lit.)
Fihirisar Refractive n20/D	1.461
Ajiye Karkashin Gas Inert	Ajiye Karkashin Gas Inert
M	Hygroscopic.Danshi Mai Mahimmanci, Jin zafi
Ruwan Solubility	Cikakkiyar Narke Cikin Ruwa
Solubility	Mai narkewa a Dimethylformamide, Alcohol
Adana Yanayin.	Wuri mai sanyi & bushewa (<5℃)
COA & MSDS	Akwai
Kashi	Haɗin kai Reagents
Alamar	Ruifu Chemical

Ƙayyadaddun bayanai:

Abubuwa	Ka'idojin dubawa	Sakamako
Bayyanar	Farin Crystalline Foda	Ya bi
Matsayin narkewa	110.0 ~ 115.0 ℃	112.0 ~ 114.0 ℃
Ruwa ta Karl Fischer	<0.50%	0.10%
Ragowa akan Ignition	<0.10%	0.04%
Tsafta (Argent Titration)	>99.0%	99.70%
Tsarkake / Hanyar Bincike	> 99.0% (HPLC)	Ya bi
Infrared Spectrum	Yayi daidai da Tsarin	Ya bi
Solubility a cikin H2O (100 MG / ml)	Mara launi zuwa Rawanin Rawaya sosai, bayyananne	Wuce
Kammalawa	An gwada samfurin kuma ya bi ƙayyadaddun da aka bayar

Kunshin/Ajiye/Jirgin ruwa:

Kunshin:Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Danshi Mai Hankali.Ajiye a cikin kwantena da aka rufe a wurin sanyi da bushe (<5℃) nesa da abubuwan da ba su dace ba.Kare daga haske da danshi.
Jirgin ruwa:Bayarwa ga duniya ta FedEx / DHL Express.Bayar da isarwa cikin sauri kuma abin dogaro.

Hanyar Gwaji:

Properties: Wannan samfurin fari crystalline foda.
2. Ƙayyadaddun abun ciki:
2.1 Instruments da reagents: potentiometric titrator, nitric acid bayani (12.5 wt%), AgNO3 misali bayani (0.1mol / L)
2.2 Samfurin shiri da aiki:
An narkar da 200 zuwa 220mg a cikin 40ml na ruwa mai narkewa, kuma bayan an ƙara 5ml na maganin nitric acid, maganin ya zama daidaitaccen narkar da nitrate na azurfa.
An daidaita ruwan zuwa ƙarshen batu.Tsarin ƙididdiga abun ciki na samfur shine kamar haka:
X = (VAgNO3*19.171)/W,
X- Adadin EDC.HCl, 100%.
V-ƙarar da aka cinye ta hanyar daidaitaccen bayani na AgNO3, ml
19.171-1ml AgNO3 daidaitaccen bayani (0.1mol / L) cinye EDC.HCl taro, mg;
W - samfurin taro, mg;
An yi hanyar sau uku a layi daya kuma an dauki matsakaici, kuma kuskuren dole ne ya wuce 0.3%.Abubuwan da ke cikin samfur yakamata su kasance> 99.0%.
3. Ƙimar narkewa: bisa ga hanyar ƙaddamar da ƙaddamarwa (Shafi VII C na Pharmacopoeia na kasar Sin 2010 edition), wurin narkewa na wannan samfurin ya kamata ya zama 110.0 ~ 115.0 ℃.
4. Ƙaddamar da abun ciki na ruwa: bisa ga hanyar auna danshi (hanyar KF) don ƙayyade, abun ciki na ruwa na wannan samfurin ya kamata ya zama <0.50%.
5. Adana: Ajiye a wuri mai duhu da sanyi (<5℃).
6. Lokacin dubawa: shekara guda

Hanyar roba:

Amfani:

Isasshen Ƙarfin: isassun wurare da masu fasaha

Sabis na Ƙwararru: Sabis na siyan tasha ɗaya

Kunshin OEM: Kunshin al'ada da alamar akwai

Bayarwa da sauri: Idan yana cikin haja, garantin isar da kwanaki uku

Ƙarfin Ƙarfi: Kula da haja mai ma'ana

Taimakon Fasaha: Akwai maganin fasaha

Sabis na Haɗa na Musamman: Ya bambanta daga gram zuwa kilos

High Quality: An kafa cikakken tsarin tabbatar da inganci

FAQ:

Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.

Manyan Kasuwanni?Sayarwa zuwa kasuwannin cikin gida, Arewacin Amurka, Turai, Indiya, Koriya, Jafananci, Australia, da sauransu.

Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.

inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.

Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.

Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.

MOQ?Babu MOQ.Karamin tsari abin karɓa ne.

Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.

Sufuri?By Express (FedEx, DHL), ta Air, ta Teku.

Takardu?Bayan sabis na tallace-tallace: COA, MOA, ROS, MSDS, da dai sauransu za a iya ba da su.

Haɗin Kan Al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.

Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.

25952-53-8 - Haɗari da Tsaro:

Lambobin haɗari
R34 - Yana haifar da konewa
R36/37/38 - Haushi da idanu, tsarin numfashi da fata.
R41 - Hadarin mummunan lalacewa ga idanu
R37 / 38 - Haushi ga tsarin numfashi da fata.
R20/21/22 - Cutarwa ta hanyar shakarwa, a cikin hulɗa da fata kuma idan an haɗiye shi.
Bayanin Tsaro
S26 - Idan ana hulɗa da idanu, kurkura nan da nan da ruwa mai yawa kuma ku nemi shawarar likita.
S36/37/39 - Sanya tufafin kariya masu dacewa, safar hannu da kariya ta ido/ fuska.
S45 - Idan akwai haɗari ko kuma idan kun ji rashin lafiya, nemi shawarar likita nan da nan (nuna alamar a duk lokacin da zai yiwu.)
S37/39 - Saka safofin hannu masu dacewa da kariya / ido
S36 - Sanya tufafin kariya masu dacewa.
ID na UN 2735 8/PG 3
WGK Jamus 3
Saukewa: RTECS FF220000
FLUKA BRAND F CODES 1-3-10
TSCA Y
Lambar 2925290090
Hazard Note Irritant
Guba LD50 na jini a cikin linzamin kwamfuta: 56mg/kg

Aikace-aikace:

1- (3-Dimethylaminopropyl) -3-Ethylcarbodiimide Hydrochloride (EDC · HCl) (CAS: 25952-53-8) wani farin crystalline foda ne, mai sauƙi deliquescent, mai narkewa cikin ruwa, mai narkewa a cikin ethanol, ana amfani dashi azaman mai kunnawa don carboxyl. ƙungiyoyi a cikin kira na amide, kuma ana amfani da su don kunna ƙungiyoyin phosphate, haɗin haɗin sunadarai da acid nucleic, da samar da immunocouplers.Ana amfani da EDC-HCl a cikin kewayon pH na 4.0-6.0 kuma ana amfani dashi akai-akai tare da N-Hydroxysuccinimide (NHS) ko N-Hydroxysulfosuccinimide sodium gishiri don inganta haɓakar haɗin gwiwa.
EDC · HCl shine carbodiimide mai narkewa da ruwa, ana amfani dashi da yawa don haɗakar peptide.Ana amfani da EDC · HCl azaman wakili mai kunnawa carboxyl.Yana taka muhimmiyar rawa don hana manyan kwayoyin halitta a cikin haɗin gwiwa tare da N-hydroxysuccinimide.Hakanan ana amfani dashi a cikin acylation na phosphoranes.
Abubuwan da ake so na ruwa mai narkewa na carbodiimide mai amfani don haɗawa suna faruwa zuwa sunadaran da polypeptides.An yi amfani da shi don gyara masu karɓar NMDA kuma azaman wakili mai ɗaukar nauyi a cikin haɗin peptide.Babban fa'idar haɗin gwiwar EDAC shine sauƙin cire reagent mai yawa da madaidaicin urea ta hanyar wankewa da tsarma acid ko ruwa.Carbodiimides yana haifar da samuwar amide bonds, acid carboxylic acid, da amines ta hanyar kunna carboxylate don samar da O-acylurea.Wannan tsaka-tsaki na iya kaiwa hari ta hanyar aminin kai tsaye don samar da amide.Ana fitar da EDAC azaman abin urea mai narkewa.
Ana iya amfani da EDC · HCl don haɓakar amides.Ana amfani da shi azaman wakili mai haɗawa a cikin haɗin esters daga acid carboxylic ta amfani da dimethylaminopyridine a matsayin mai kara kuzari.
Akwai manyan abubuwa guda uku da aka saba amfani da su: DCC, DIC da EDC·HCl.Yin amfani da irin wannan nau'in nau'in nau'i na nau'i na kullun yana buƙatar ƙari na acylation catalysts ko activators, irin su DMAP, HOBt, da dai sauransu Tun da ƙarin tsaka-tsaki na acid zuwa carbodiimide a farkon mataki na amsawa bai tsaya ba, idan acylation. Ba a amfani da mai kara kuzari don canza shi zuwa ester mai aiki daidai ko amide mai aiki, za a sake tsara shi zuwa daidaitaccen samfurin urea (Hanyar B).Mai kunna kwandon ruwa: Akwai nau'ikan na'urar kunnawa da aka saba amfani da ita.A halin yanzu, 4-N, N-dimethylpyridine (DMAP) an yi amfani dashi sosai don ƙaddamar da halayen acylation daban-daban.Wani lokaci ana iya amfani da 4-PPY lokacin da tasirin DMAP ba shi da kyau.Dangane da wallafe-wallafen da suka dace, ƙarfin ƙarfin sa ya kai kusan sau dubu fiye da DMAP.Daga cikin na'urori uku da aka saba amfani da su, DCC da DIC sun fi rahusa.Gabaɗaya ana amfani da DCC da DMAP tare.Daya daga cikin manyan rashin amfani da DCC shi ne cewa sauran samfurin na dauki, dicyclohexylurea, yana da karamin solubility a cikin general kwayoyin lokaci amma shi ne dan kadan soluble, don haka yana da wuya a cire shi sosai ta hanyar da aka saba amfani da tsarkakewa hanyoyin, recrystallization. chromatography shafi, da dai sauransu;saboda solubility na dicyclohexylurea a cikin ether kadan ne fiye da sauran sauran kaushi, saboda haka, jiyya na irin wannan dauki gaba daya evaporates da sauran ƙarfi dauki da kuma ƙara ether, da kuma tace mafi yawan dicyclohexylurea kafin a ci gaba da jiyya.Saboda diisopropylurea da DIC ke samarwa yana da ingantacciyar narkewa a cikin abubuwan kaushi na halitta gabaɗaya, ana amfani da shi gabaɗaya a cikin haɗaɗɗen sinadarai mai ƙarfi-lokaci.A halin yanzu ana amfani da EDCI mafi yawa a cikin sinadarai na magani.Ɗaya daga cikin manyan halayensa shine cewa urea da aka samar bayan an dauki shi yana da ruwa mai narkewa kuma yana da sauƙin wankewa.Gabaɗaya, EDCI yana haɗuwa tare da HOBt (bayanin kula: wannan amsawar HOBt gabaɗaya ba ta da makawa, in ba haka ba yana iya haifar da ƙarancin yawan amfanin ƙasa).Wani lokaci idan matsananciyar matsayi na acid yana da girma ko kuma akwai ƙungiyar janyewar lantarki, amsawar za ta kasance a cikin mataki na ester mai aiki (ester mai aiki yana da siginar taro mai ƙarfi kuma MS ko LC-MS zai iya gano shi).