Entecavir CAS 142217-69-4 API Babban Ka'idar Anti-HBV
Samar da Mai ƙira tare da Tsaftataccen Tsafta da Tsayayyen inganci
Sunan Chemical: Entecavir
Saukewa: 142217-69-4
Magungunan rigakafi da ake amfani da su wajen maganin cutar Hepatitis B
API High Quality, Kasuwancin Kasuwanci
Sunan Sinadari | Entecavir |
Makamantu | 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3- (hydroxymethyl) -2-methylenecyclopentyl]-6H-purin-6-daya |
Lambar CAS | 142217-69-4 |
Lambar CAT | RF-API80 |
Matsayin Hannun jari | A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram |
Tsarin kwayoyin halitta | Saukewa: C12H15N5O3 |
Nauyin Kwayoyin Halitta | 277.28 |
Matsayin narkewa | 249.0 ~ 252.0 ℃ |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Farin Crystalline Foda |
Gano IR | Bakan sharar infraed na samfurin gwajin dole ne ya kasance daidai da ma'aunin tunani |
Bayanin HPLC | Lokacin riƙewar samfurin gwajin yayi daidai da na ƙa'idar tunani |
pH | 5.5 ~ 7.5 |
Takamaiman Juyawar gani | +24.0°-+28.0° (DMF: MeOH=1:1 C=1%) |
Abubuwa masu alaƙa | |
Jimlar ƙazanta | ≤0.30% |
Matsakaicin Tsabtace Guda Daya | ≤0.10% |
Enantiomer | ≤0.20% |
Ragowar Magani | |
Methanol | ≤0.30% |
Dichloromethane | ≤0.06% |
n-Hexane | ≤0.029% |
Tetrahydrofuran | ≤0.072% |
N, N-Dimethylformamide | ≤0.088% |
Toluene | ≤0.089% |
Abubuwan Ruwa | 5.8% ~ 6.5% |
Ragowa akan Ignition | ≤0.10% |
Karfe masu nauyi | ≤20ppm |
Assay | 98.0% ~ 102.0% (C12H15N5O3 da aka lissafta akan tushen rashin ruwa) |
Girman Barbashi | D90: ≤100µm |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | API, Magungunan rigakafi da aka yi amfani da su wajen maganin Cutar Hepatitis B |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Entecavir wani sabon ƙarni ne na guanine nucleoside analogues na baka magani don lura da cutar Hepatitis B Virus (HBV) kamuwa da cuta, yafi domin lura da manya marasa lafiya tare da kwayar cutar kwafi aiki da serum transaminase ya ci gaba da karuwa, ko hanta nama ga pathological ayyuka na kullum hepatitis B. , A halin yanzu cutar ta ragu da sauri kuma mafi ƙarfi, mafi ƙarancin maye gurbi na analogues na nucleoside.Bayanai sun nuna cewa daban-daban a cikin marasa lafiya tare da ciwon hanta na kullum, ciki har da nucleoside naive da nucleoside da aka bi da su da kuma hanta cirrhosis marasa lafiya, ta yin amfani da allunan entecavir da kyau a cikin jiyya na iya sarrafa cutar da sauri da sauƙi zuwa maganin ƙarshen gaskiya, wato cutar hepatitis B ba tare da aunawa ba;ta hanyar riko da jiyya, za a iya isa ga wani babba rabo daga marasa lafiya a karshen jiyya gamsuwa, wato e antigen serology tuba, wasu marasa lafiya iya ko da isa ga manufa domin lura da karshen, wato surface antigen korau.