Entecavir Monohydrate CAS 209216-23-9 API Factory High Quality Antiviral Hepatitis B Kamuwa
Samar da Mai ƙira tare da Tsaftataccen Tsafta da Tsayayyen inganci
Sunan Chemical: Entecavir Monohydrate
Saukewa: 209216-23-9
Ana amfani da shi wajen maganin cutar Hepatitis B
API High Quality, Kasuwancin Kasuwanci
Sunan Sinadari | Entecavir Monohydrate |
Makamantu | Entecavir Hydrate;9-[(1S,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl] guanine Monohydrate |
Lambar CAS | 209216-23-9 |
Lambar CAT | RF-API79 |
Matsayin Hannun jari | A Hannun jari, Ma'aunin Samfuran Har zuwa Daruruwan Kilogram |
Tsarin kwayoyin halitta | Saukewa: C12H17N5O4 |
Nauyin Kwayoyin Halitta | 295.3 |
Matsayin narkewa | > 220 ℃ |
Yawan yawa | 1.81 |
Yanayin jigilar kaya | An aika Karkashin Zazzabin yanayi |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Fari ko Kusan Farin Crystalline Foda |
Solubility | Mai Soluble Kyauta a Dimethylformamide, Dan Soluble a Ruwa, Ethanol da Methanol |
Gano IR | Bakan samfurin yayi daidai da na ma'aunin tunani |
Bayanin HPLC | Lokacin riƙewar samfurin gwajin yayi daidai da na ƙa'idar tunani |
Abubuwan Ruwa (na KF) | 5.5% ~ 6.5% |
Takamaiman Juyawar gani | +24.0° zuwa +30.0° (DMF: MeOH=1:1 C=1%) (akan wani abu mara ruwa) |
Ragowa akan Ignition | ≤0.10% |
Abubuwa masu alaƙa | |
Furontecavir | ≤0.10% |
Entecavir 1-Epimer | ≤0.10% |
Entecavir 3-Epimer | ≤0.10% |
8-Methyoxy Entecavir | ≤0.10% |
Entecavir 4-Epimer | ≤0.10% |
8-Hydroxy Entecavir | ≤0.10% |
4-Dimethylsilyl Entecavir | ≤0.10% |
Abubuwan da suka danganci Entecavir A | ≤0.10% |
Duk Wani Tsaftar Da Ba A Fayyace Ba | ≤0.10% |
Jimlar ƙazanta | ≤0.30% |
Ragowar Magani | |
Methanol | ≤600ppm |
Dichloromethane | ≤300ppm |
Ethyl acetate | ≤1000ppm |
Tetrahydrofuran | ≤720ppm |
Toluene | ≤890ppm |
Benzyl chloride | ≤1000ppm |
Benzyl Alcohol | ≤1000ppm |
Iyakar Microbial | |
Jimlar Ƙididdigar Aerobic | ≤100cfu/g |
Yisti da Molds | ≤10cfu/g |
Escherichia Coli | Bai kamata a Gano ba |
Karfe masu nauyi | ≤10ppm |
Assay | 98.0% ~ 102.0% (HPLC; akan tushen anhydrous) |
Girman Barbashi | 95% na barbashi yakamata su kasance cikin 125um |
Matsayin Gwaji | Matsayin Kasuwanci;Amurka Pharmacopoeia (USP) Standard |
Amfani | Magungunan rigakafi da ake amfani da su wajen maganin cutar Hepatitis B |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Entecavir Monohydrate (CAS 209216-23-9) magani ne na baki wanda ake amfani dashi wajen maganin kamuwa da cutar Hepatitis B Virus (HBV).Entecavir Monohydrate shine analog na nucleoside (fiye da musamman, analog na guanine) wanda ke hana jujjuya rubutu, kwafin DNA da kwafi a cikin vira.Wani sabon nau'in cyclopentyl acyl guanosin anti-Hepatitis B kwayar kwayoyi ne tare da tasirinsa na harhada magunguna kamar Entecavir.An yi amfani da shi a asibiti don maganin balagaggu na Hepatitis B na manya wanda ke da kwayar cutar kwayar cuta mai aiki, ƙara yawan transaminase ALT ko raunuka masu aiki da aka nuna daga tarihin hanta.Entecavir Monohydrate shine mai hanawa mai ƙarfi da zaɓi na HBV, tare da EC50 na 3.75 nM a cikin tantanin halitta HepG2.Entecavir shine mai hana fassarar fassarar.Yana hana cutar Hepatitis B (HBV) yawaita da kuma rage yawan kwayar cutar a jiki.