Epalrestat CAS 82159-09-9 Tsarkake> 99.5% (HPLC) Factory
Shanghai Ruifu Chemical Co., Ltd. shine babban kamfani na Epalrestat (CAS: 82159-09-9) tare da inganci.Ruifu Chemical na iya samar da isar da sako na duniya, farashi mai gasa, ƙanana da yawa da ake samu.Sayi Epalrestat,Please contact: alvin@ruifuchem.com
| Sunan Sinadari | Epalrestat |
| Makamantu | Epalrest;ONO-2235;Eabeth;Kinedak;Sorbistat;(5Z) -5-[(2E) -2-Methyl-3-phenyl-2-propen-1-ylidene] -4-oxo-2-thioxo-3-Thiazolidineacetic Acid;2-[(5Z) -5-[(E) -3-Phenyl-2-methylprop-2-enylidene] - 4-oxo-2-thioxo-3-thiazolidinyl] acetic acid;(E, E) -2-[5- (2-Methyl-3-phenyl-prop-2-enylidene) -4-oxo-2-sulfanylidene-thiazolidin-3-yl] acetic acid |
| Matsayin Hannun jari | A Stock, Mass Production |
| Lambar CAS | 82159-09-9 |
| Tsarin kwayoyin halitta | Saukewa: C15H13NO3S2 |
| Nauyin Kwayoyin Halitta | 319.39 g/mol |
| Matsayin narkewa | 222.0 zuwa 226.0 ℃ |
| Yawan yawa | 1.43± 0.10 g/cm3 |
| Solubility | DMSO 2 mg/mL Ruwa <1 mg/mL ethanol <1 mg/mL |
| Adana Yanayin. | Wuri mai sanyi & bushe (-20 ℃) |
| COA & MSDS | Akwai |
| Kashi | API |
| Alamar | Ruifu Chemical |
| Abubuwa | Ka'idojin dubawa | Sakamako |
| Bayyanar | Orange zuwa Orange Red Crystalline Foda | Ya bi |
| Ganewa | Daidai da daidaitattun lokacin riƙewar HPLC | Wuce |
| Matsayin narkewa | 222.0 zuwa 226.0 ℃ | 222.4 ~ 224.3 ℃ |
| Asara akan bushewa | <0.50% | 0.04% |
| Ragowa akan Ignition | <0.20% | 0.03% |
| Karfe masu nauyi (Pb) | ≤20ppm | <20ppm |
| Jimlar ƙazanta | ≤0.50% | 0.20% |
| Tsarkake / Hanyar Bincike | > 99.5% (HPLC) | 99.8% |
| Infrared Spectrum | Yayi daidai da Tsarin | Ya bi |
| Kammalawa | An gwada samfurin kuma ya bi ƙayyadaddun da aka bayar | |
Kunshin:Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wurin sanyi da bushe (-20 ℃) nesa da abubuwan da ba su dace ba.Kare daga haske da danshi.
Jirgin ruwa:Bayarwa ga duniya ta FedEx / DHL Express.Bayar da isarwa cikin sauri kuma abin dogaro.
Yadda ake siya?Da fatan za a tuntuɓiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Kwarewar Shekaru 15?Muna da fiye da shekaru 15 na gwaninta a cikin ƙira da fitarwa na matsakaicin matsakaicin magunguna masu inganci ko sinadarai masu kyau.
Manyan Kasuwanni?Sayarwa zuwa kasuwannin cikin gida, Arewacin Amurka, Turai, Indiya, Koriya, Jafananci, Australia, da sauransu.
Fa'idodi?Babban inganci, farashi mai araha, sabis na ƙwararru da tallafin fasaha, bayarwa da sauri.
inganciTabbaci?Tsananin kula da ingancin inganci.Kayan aikin ƙwararru don bincike sun haɗa da NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, gwajin ƙayyadaddun ƙwayoyin cuta, da sauransu.
Misali?Yawancin samfurori suna ba da samfurori kyauta don ƙima mai kyau, farashin jigilar kaya ya kamata a biya ta abokan ciniki.
Binciken Masana'antu?Ma'aikata duba maraba.Da fatan za a yi alƙawari a gaba.
MOQ?Babu MOQ.Karamin tsari abin karɓa ne.
Lokacin Bayarwa? Idan cikin hannun jari, garantin isar da kwana uku.
Sufuri?By Express (FedEx, DHL), ta Air, ta Teku.
Takardu?Bayan sabis na tallace-tallace: COA, MOA, ROS, MSDS, da dai sauransu za a iya ba da su.
Haɗin Kan Al'ada?Zai iya ba da sabis na haɗawa na al'ada don dacewa da buƙatun bincikenku.
Sharuɗɗan Biyan kuɗi?Za a fara aiko da daftari na Proforma bayan tabbatar da oda, an rufe bayanan bankin mu.Biya ta T/T (Telex Transfer), PayPal, Western Union, da dai sauransu.
Bayanan Bayani na UN2811
WGK Jamus 3
Saukewa: RTECS XJ5131855
Matsayin Hazard 6.1
Rukunin tattarawa II
Epalrestat (CAS: 82159-09-9) shine mai hana aldose reductase na biyu wanda za'a gabatar a duk duniya kuma na farko da aka ƙaddamar a Japan.Ana nuna Epalrestat don maganin neuropathy na ciwon sukari.Har ila yau, ana bincikar cutar ciwon sukari na retinopathy da nephropathy.Epalrestat shine mai hana aldose reductase tare da IC50 na 72 nM.
Epalrestat yana hana Aldose Reductase (AR) shiga cikin ƙayyadaddun ƙimar matakin canza glucose zuwa sorbitol a ƙarƙashin yanayin hyperglycemic.Aldose reductase ya kasance makasudin binciken bincike na asibiti da yawa don kula da ciwon sukari neuropathy da retinopathy.Epalrestat magani ne da aka yarda da shi a Japan da Indiya, ana amfani da shi don maganin neuropathy na ciwon sukari.
Ana amfani da Epalrestat don hanawa, ingantawa, da kuma kula da neuropathy na gefe (launi, zafi), rawar jiki, da rashin lafiyar zuciya mai alaƙa da ciwon sukari.
Epalrestat a matsayin wakilinsa na miyagun ƙwayoyi yana rage ƙwayar intracellular na fructose da sorbitol ta hanyar hana ayyukan aldose reductase, mayar da Na +-K +-ATPase da aikin inositol, yana ƙara NO samu a cikin sel endothelial, yana hana gina jiki kinase C hanyar siginar, endothelial glucose adhesion, high adhesion. tsaka-tsaki neutrophil da endothelial adhesion factor magana da kuma rage carboxymethyl lysine kayayyakin a cikin masu ciwon sukari, don haka zalunta cututtuka irin su ciwon sukari da kuma rikitarwa.
