Ethyl (S) -4-Chloro-3-hydroxybutyrate CAS 86728-85-0 Atorvastatin Calcium Intermediate
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Sunan Sinadari | Ethyl (S) -4-Chloro-3-hydroxybutyrate |
Makamantu | (S)-4-Chloro-3-hydroxybutyric Acid Ethyl Ester |
Lambar CAS | 86728-85-0 |
Lambar CAT | Saukewa: RF-PI139 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C6H11ClO3 |
Nauyin Kwayoyin Halitta | 166.6 |
Yawan yawa | 1.19 g/ml a 25 ℃ (lit.) |
Fihirisar Refractive | n20/D 1.453 (lit.) |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Mara Launi zuwa Kodadden Ruwan Rawaya |
Tsarkake / Hanyar Bincike | ≥98.0% (GC) |
Danshi (KF) | ≤0.50% |
Ethyl-4-Chloro aceto acetate | ≤0.50% |
Matsayin Gwaji | Matsayin Kasuwanci |
Amfani | Matsakaicin Magunguna;Tsarin Halitta |
Ethyl (S)-4-Chloro-3-hydroxybutyrate (CAS: 86728-85-0)
Hanyar bincike
Bayani
Ɗauki kimanin 10ml samfurin a cikin farantin gilashi mai tsabta da bushe kuma a duba.
Takamaiman juyawa
Canja wurin daidai game da 1.0g na samfur zuwa 100ml volumetric flask kuma narkar da a ciki10 ml na chloroform, sannan a tsoma shi da chloroform zuwa 100ml a gauraya.
Auna jujjuyawar gani na samfurin gwajin a 25ºC da 589nm tsayin raƙuman ruwaƙididdige ƙayyadaddun juyawa kamar yadda aka ba da dabara.
[a]25D = (v×a)/[w×(1-b)]
[a]25D: takamaiman juyawa na gwajisamfurin;α: juyawar da aka lura a cikidigiri na kusurwa;w: nauyin samfurin (g);
v: girma (ml);
b: Abubuwan ruwa (%)
Tsarki (na GC)
Yanayi na chromatographic: Gas chromatography sanye take da harshen wutaionization detector
Shafin: SE-54, 30m×0.35×0.25µm
Zafin tanda: Zazzabi na farko 120 ℃, Riƙe lokaci na 2min
Ramp: 20 ℃/min
Zazzabi: 250 ℃, Riƙe lokaci na 2min
Injector zafin jiki: 250 ℃
Zazzabi mai ganowa: 250 ℃ (FID)
Girman allura: 0.2µl
Samfurin bayani: tsarma 1ml A4 tare da 1ml acetone.
Tsari: Allurar 0.2µl na acetone a matsayin fanko kuma yi rikodin chromatogram.A cikinchromatogram da aka samo daga diluent bai kamata ya zama wani tsangwama a cikinlokacin riƙe babban kololuwa da ƙazanta kololuwa.Fiye da allurar maganin samfurin a cikiKwafi a cikin chromatograph kuma yi rikodin chromatogram.Rahoton Tsarkakewasamfurin ta hanyar daidaita yanayin yanki.
Kunshin: Kwalba, Ganga, 25kg/ Ganga, ko bisa ga buƙatun abokin ciniki.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
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Shanghai Ruifu Chemical Co., Ltd. shine babban masana'anta kuma mai samar da Ethyl (S) -4-Chloro-3-hydroxybutyrate (CAS: 86728-85-0) tare da babban inganci, matsakaici ne yawanci a cikin haɗin Atorvastatin. Calcium (CAS: 134523-03-8).
Calcium Atorvastatin (CAS: 134523-03-8) [sunan kasuwanci: Lipitor] ana yin nuni da shi don maganin cututtukan zuciya da jijiyoyin jini da dyslipidemia saboda tasirinsa na rage cholesterol a cikin jini.Atorvastatin yana aiki da farko a cikin hanta.Rage matakan cholesterol na hanta yana ƙara haɓaka ƙwayar hanta na cholesterol kuma yana rage matakan cholesterol na plasma.Lipitor, tun 1996, ya zama mafi kyawun sayar da magunguna a duniya har zuwa wannan lokacin.
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