Etravirine TMC-125 CAS 269055-15-4 Assay ≥99.0% (HPLC) API Factory High Tsabta
Mai ƙera tare da Babban Tsafta da Ƙarfin Ƙarfi
Sunan Chemical: EtravirineTMC-125)
Saukewa: 269055-15-4
API High Quality, Kasuwancin Kasuwanci
Sunan Sinadari | Etravirine |
Makamantu | Saukewa: TMC-125 |
Lambar CAS | 269055-15-4 |
Lambar CAT | RF-API54 |
Matsayin Hannun jari | A cikin Hannun jari, Ma'aunin samarwa Har zuwa Ton |
Tsarin kwayoyin halitta | Saukewa: C20H15BrN6O |
Nauyin Kwayoyin Halitta | 435.28 |
Yawan yawa | 1.439 g/cm 3 |
Yanayin jigilar kaya | Karkashin Zazzabi |
Alamar | Ruifu Chemical |
Abu | Ƙayyadaddun bayanai |
Bayyanar | Farin Soyayyen Foda |
Ganewa | By IR, HPLC |
Matsayin narkewa | 211.0 ~ 216.0 ℃ |
Abubuwan Ruwa | ≤0.50% |
Ragowa akan Ignition | ≤0.20% |
Karfe masu nauyi | ≤20ppm |
Duk Wani Rashin Tsabtace Guda Daya | ≤0.50% |
Jimlar ƙazanta | ≤1.0% |
Assay | ≥99.0% (HPLC) |
Matsayin Gwaji | Matsayin Kasuwanci |
Kunshin: Bottle, Aluminum tsare jakar, Kwali drum, 25kg / Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske, danshi da kamuwa da kwari.
Etravirine (TMC-125) (CAS 269055-15-4) wani ƙarni na biyu ne wanda ba na baya-bayan nan ba na nucleoside reverse transcriptase inhibitor (NNRTI) wanda aka yi amfani da shi don maganin cutar kanjamau.An nuna shi don amfani da shi tare da sauran magungunan rigakafin cutar HIV-1 don magance kamuwa da cutar HIV-1 a cikin ƙwararrun ƙwararrun marasa lafiya waɗanda ke da shaidar kwafin ƙwayar cuta da ƙwayar cutar HIV-1 da ke jure wa NNRTIs da ake da su a halin yanzu da sauran magungunan antiretroviral.NNRTIs, tare da nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs/NtRTIs), su ne muhimman sassa na tsarin haɗin gwiwar da ake amfani da su a halin yanzu don magance cutar HIV-1.NRTIs/NtRTIs suna aiki ta hanyar yin gasa tare da sinadarai na nucleotide na baya-bayan nan don haɗawa cikin DNA na hoto ko bidiyo mai zagaya yanar gizo da sauri.Sabanin haka, NNRTIs suna ɗaure zuwa wurin allosteric na enzyme kuma suna tarwatsa aikin DNA polymerase ta hanyar haifar da canje-canje masu daidaituwa zuwa wurin catalytic.